Postdoctoral Research Scientist

Research position at the level of Postdoctoral Research Scientist is available at the Center for Radiological Research (CRR.columbia.edu) at Columbia University Irving Medical Center in New York to investigate the effect of acute high-dose radiation exposure on the gut microbiome and its impact on gastrointestinal (GI) tract injury. We have developed an orally administered radiomitigator that is specifically targeted to the mucosal surface of the GI tract to potentially alleviate the deleterious effects of radiation in animal models. The major focus of this research study will be to perform longitudinal structural and functional studies to determine the impact of radiation, on GI architectural integrity, commensal gut microbiota composition and diversity, and microbiome-host interactions after drug treatment/irradiation using conventional and human gnotobiotic mouse models, flow cytometry, and ELISA-based assays. Additionally, mechanistic studies will be performed to determine the mode of action of the radiomitigator using transgenic animal models and human cell-based assays.

The team is highly multidisciplinary encompassing the fields of molecular, cell, and radiation biology, biophysics, immunology, and microbiome genomics, so good communication and strong organization skills are essential.

Qualifications
PhD in any of the following: Pharmacology, Physiology, Toxicology, Cell Biology, Radiobiology, Immunology, Genomics, or a related field. Prior research experience in microbial-host interactions, and/or mouse models is desirable but not required.

Application procedure

Your completed application must be submitted through  https://academic.careers.columbia.edu/

Job ID: #110972

Columbia University is an Equal Opportunity Employer / Disability / Veteran