Post-Doc Research Associate - Dr. Frankowski's lab

University of North Carolina, United States

Updated: about 2 years ago
Location: Chapel Hill, NORTH CAROLINA
Job Type: FullTime
Deadline: ; ;

Posting Information
Department SOP-CICBDD - 452101
Posting Open Date 01/06/2022
Application Deadline
Open Until Filled Yes
Position Type Postdoctoral Scholar
Position Title Post-Doc Research Associate - Dr. Frankowski's lab
Vacancy ID PDS003324
Full-time/Part-time Full-Time Temporary
Hours per week 40
FTE 1
Work Location Chapel Hill, NC
Position Location North Carolina, US
Hiring Range Dependent on Experience and Qualifications.
Proposed Start Date 02/15/2022
Estimated Duration of Appointment 12 Months

Primary Purpose of Organizational Unit
The UNC Eshelman School of Pharmacy (www.pharmacy.unc.edu) is one of five health science schools (Pharmacy, Nursing, Dentistry, Public Health, Medicine) at the University of North Carolina at Chapel Hill and is one of the oldest health science academic programs at Chapel Hill. The School teaches approximately 600 PharmD students, 100 PhD students, and 20 Master’s students. The School has built a reputation for its continued pursuit of excellence, rigorous education and training programs, cutting-edge multidisciplinary research, progressive pharmacy practices, efficient business operations, and its outstanding faculty, staff, and students. The School was named the number one School of Pharmacy in the U.S. by the U.S. News and World Report. The School has experienced unprecedented growth and success and continues to strategically position itself for sustained impact, as articulated in the School’s Strategic Plan (https://pharmacy.unc.edu/about/ospa/strategic-plan/)
Our vision is to be the preeminent school of pharmacy where leaders in practice, education, and research are developed and nurtured. We are Advancing Medicine for Life through innovation and collaboration in pharmacy practice, education, research, and public service.
Position Summary
This position is focused on the design and construction of novel molecules for selective dopamine modulation. We are investigating molecules that interact at allosteric sites on dopamine receptors, a novel approach to dopamine regulation and a potential therapeutic for Parkinson’s disease, substance use disorder, schizophrenia and dementia. This project is a collaboration with the Sibley Lab (NIH/NINDS), who are responsible for all assays and screening. Thus, this position is dedicated to the development of new synthetic methods and routes to the target scaffolds and their application to optimize these novel ligands. Research is conducted within the highly collaborative environment of the UNC Center for Integrative Chemical Biology and Drug Discovery. http://frankowskilab.web.unc.edu/
Duties: 
Perform research in synthetic organic chemistry (75%). The primary duty is to design and carry out experiments leading to the synthesis of biologically relevant molecules. The following subtasks are associated with his duty:
 Carry out literature searches relevant to the research topic.
* Cleaning, organization, and maintenance of the laboratory and equipment contained therein.
* Understand the up-to-date laboratory safety protocols and employ them in the course of all work. Use proper personal protective equipment at all times.
* Keep detailed notes and records pertaining to all research work and be comfortable with the required use of electronic notebook software.
 * Interpreting data and using results to drive additional experimental design.
* Attend and participate in scientific group meetings, departmental seminars, and problem sessions (10%).
* Contribute to the preparation and submission of reports and publications related to research (15%).
* Report results at external, national scientific meetings.
Minimum Education and Experience Requirements
Ph. D. in organic chemistry, medicinal chemistry or in related discipline
Required Qualifications, Competencies, and Experience
Ph. D. in organic chemistry, medicinal chemistry or in related discipline
Preferred Qualifications, Competencies, and Experience
Preferred:
* Strong organic synthesis skills, as evidenced by peer reviewed publications. 
* Experience with a wide range of purification techniques (e.g. flash chromatography, HPLC, distillation, etc.)
* Evidence of collaborative research experience
* Experience in the construction of heterocyclic molecules.
* Extensive familiarity with NMR acquisition and spectral analysis.
Special Physical/Mental Requirements
Must comply with all environmental health and safety best practices including proper use of all personal protective equipment
Special Instructions
For information on UNC Postdoctoral Benefits and Services click here
 
Quick Link https://unc.peopleadmin.com/postings/219145

Department Contact Name and Title Alekya Battula, HR Consultant
Department Contact Telephone or Email [email protected]
Postdoctoral Affairs Contact Information
If you experience any problems accessing the system or have questions about the application process, please contact the University’s Equal Employment Opportunity office at (919) 966-3576 or send an email to [email protected]. 
 
Please note: The Equal Employment Opportunity office will not be able to provide specific updates regarding position or application status.
Equal Opportunity Employer Statement
The University of North Carolina at Chapel Hill is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender, gender expression, gender identity, genetic information, race, national origin, religion, sex, sexual orientation, or status as a protected veteran.
The School’s vision is grounded in our aspiration to be a diverse and inclusive community of people who accelerate new thinking and ideas in education, research, and practice that have a positive impact on human health worldwide. We envision a school that reflects, in all its dimensions, the population it serves.

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