Research Associate (Fixed Term)

Salary: £32,816-£40,322

Reference: SC27376

Closing date: 10 August 2021

Investigating alpha1-antitrypsin phase transition in the endoplasmic reticulum

We are seeking a post-doctoral research associate to join the lab of Professor Stefan  Marciniak in the Cambridge Institute for Medical Research (CIMR) to study the role of protein phase transitions in alpha1-antitrypsin deficiency.  The Marciniak lab combines cell biology, biochemistry, and translational medicine to understand the role of proteotoxicity in human disease https://www.cimr.cam.ac.uk/staff/professor-stefan-marciniak .

The Alpha1-Foundation-funded post is at research associate (post-doc) level and so a PhD in a relevant discipline and expertise in mammalian cell culture are essential. Expertise in proteomics, flow cytometry, confocal microscopy or stem cells would be advantageous.

The successful applicant will use a variety of cutting-edge microscopy and proteomics techniques to understand the effects of protein phase transitions on function of the endoplasmic reticulum of iPSC-derived hepatocytes.

Fixed-term: The funds for this post are available for 2 years in the first instance.

To apply online for this vacancy and to view further information about the role, please visit: http://www.jobs.cam.ac.uk/job/30561 .

Please contact Professor Stefan Marciniak at [email protected] and Dr Joe Chambers at [email protected] for further information.

Please quote reference SC27376 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.