Research Laboratory Technician Position in Diabetes/Immunometabolism Lab

Updated: 2 months ago
Job Type: FullTime
Deadline: 19 Apr 2024

22 Mar 2024
Job Information
Organisation/Company

University of Basel
Research Field

Chemistry » Biochemistry
Medical sciences » Other
Researcher Profile

First Stage Researcher (R1)
Country

Switzerland
Application Deadline

19 Apr 2024 - 21:59 (UTC)
Type of Contract

Temporary
Job Status

Full-time
Hours Per Week

38
Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme
Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

The research group Diabetes under guidance of Prof. Marc Donath offers a Research Laboratory Technician position in the context of endocrinology/metabolism/diabetes. This position will be based in the Department of Biomedicine (https://biomedizin.unibas.ch ) at the University of Basel/University Hospital Basel, Switzerland.

The Diabetes group studies the pathogenesis of type 2 diabetes and in particular how components of the immune system interact with endocrine pathways to manage energy distribution and tissue metabolism. We focus on hormones secreted by pancreatic islet cells, tissue macrophages and the pathological/physiological role of the macrophage-derived cytokine Interleukin-1 beta.

Support PhD students in their projects with hands-on work. Develop and run assays. Manage data. Help to run the lab by performing common lab task such as ordering and re-stocking materials. Show interest in, discuss and provide input to various research projects.

The candidate is expected to be have a Laboratory technician apprenticeship or a Bachlor's Degree, be enthusiastic about immune-metabolic research and interact and exchange with other members of the lab. The candidate should be comfortable working with mice and prior experience with in vivo work are of advantage. The primary lab language is English and good written and oral skills are required.

Position in an international and competitive environment where basic and clinical research meet. The applied research models are predominantly genetically-modified in vivo and ex vivo mouse models in combination with pharmacological tools. Other state-of-the-art lab techniques applied are flow-cytometry, histology, qPCR as well as various protein and enzyme activity assays.

Recent relevant publications:

  • Prohormone convertase 1/3 deficiency causes obesity due to impaired proinsulin processing. Meier et al. Nat Comm 2022. PMID: 35963866
  • The cephalic phase of insulin release is modulated by IL-1β. Wiedemann et al. Cell Metab 2022. PMID: 35750050
  • Postprandial Hypoglycemia in Patients after Gastric Bypass Surgery Is Mediated by Glucose-Induced IL-1β. Hepprich et al. Cell Metab 2020. PMID: 32197070
  • Postprandial macrophage-derived IL-1β stimulates insulin, and both synergistically promote glucose disposal and inflammation. Dror et al. Nat Immunol 2017. PMID: 28092375

Application / Contact

Please include a CV and a motivation letter in your initial inquiry.
Daniel Zeman-Meier, [email protected]


Requirements
Research Field
Chemistry
Years of Research Experience
1 - 4

Research Field
Medical sciences
Years of Research Experience
1 - 4

Additional Information
Website for additional job details

https://academicpositions.com

Work Location(s)
Number of offers available
1
Company/Institute
University of Basel
Country
Switzerland
City
Basel
Postal Code
CH-4003
Street
Petersplatz 1

Where to apply
Website

https://academicpositions.com/ad/university-of-basel/2024/research-laboratory-t…

Contact
City

Basel
Website

https://www.unibas.ch/en.html
Postal Code

CH-4003

STATUS: EXPIRED

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