22 Mar 2024
Job Information
- Organisation/Company
University of Basel- Research Field
Chemistry » Biochemistry
Medical sciences » Other- Researcher Profile
First Stage Researcher (R1)- Country
Switzerland- Application Deadline
19 Apr 2024 - 21:59 (UTC)- Type of Contract
Temporary- Job Status
Full-time- Hours Per Week
38- Is the job funded through the EU Research Framework Programme?
Not funded by an EU programme- Is the Job related to staff position within a Research Infrastructure?
No
Offer Description
The research group Diabetes under guidance of Prof. Marc Donath offers a Research Laboratory Technician position in the context of endocrinology/metabolism/diabetes. This position will be based in the Department of Biomedicine (https://biomedizin.unibas.ch ) at the University of Basel/University Hospital Basel, Switzerland.
The Diabetes group studies the pathogenesis of type 2 diabetes and in particular how components of the immune system interact with endocrine pathways to manage energy distribution and tissue metabolism. We focus on hormones secreted by pancreatic islet cells, tissue macrophages and the pathological/physiological role of the macrophage-derived cytokine Interleukin-1 beta.
Support PhD students in their projects with hands-on work. Develop and run assays. Manage data. Help to run the lab by performing common lab task such as ordering and re-stocking materials. Show interest in, discuss and provide input to various research projects.
The candidate is expected to be have a Laboratory technician apprenticeship or a Bachlor's Degree, be enthusiastic about immune-metabolic research and interact and exchange with other members of the lab. The candidate should be comfortable working with mice and prior experience with in vivo work are of advantage. The primary lab language is English and good written and oral skills are required.
Position in an international and competitive environment where basic and clinical research meet. The applied research models are predominantly genetically-modified in vivo and ex vivo mouse models in combination with pharmacological tools. Other state-of-the-art lab techniques applied are flow-cytometry, histology, qPCR as well as various protein and enzyme activity assays.
Recent relevant publications:
- Prohormone convertase 1/3 deficiency causes obesity due to impaired proinsulin processing. Meier et al. Nat Comm 2022. PMID: 35963866
- The cephalic phase of insulin release is modulated by IL-1β. Wiedemann et al. Cell Metab 2022. PMID: 35750050
- Postprandial Hypoglycemia in Patients after Gastric Bypass Surgery Is Mediated by Glucose-Induced IL-1β. Hepprich et al. Cell Metab 2020. PMID: 32197070
- Postprandial macrophage-derived IL-1β stimulates insulin, and both synergistically promote glucose disposal and inflammation. Dror et al. Nat Immunol 2017. PMID: 28092375
Application / Contact
Please include a CV and a motivation letter in your initial inquiry.
Daniel Zeman-Meier, [email protected]
Requirements
- Research Field
- Chemistry
- Years of Research Experience
- 1 - 4
- Research Field
- Medical sciences
- Years of Research Experience
- 1 - 4
Additional Information
- Website for additional job details
https://academicpositions.com
Work Location(s)
- Number of offers available
- 1
- Company/Institute
- University of Basel
- Country
- Switzerland
- City
- Basel
- Postal Code
- CH-4003
- Street
- Petersplatz 1
Where to apply
- Website
https://academicpositions.com/ad/university-of-basel/2024/research-laboratory-t…
Contact
- City
Basel- Website
https://www.unibas.ch/en.html- Postal Code
CH-4003
STATUS: EXPIRED
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