The Persat lab located in the School of Life Science at EPFL, Switzerland, invites applications for a postdoctoral position in Microbiology.
The lab focuses on understanding how bacteria sense and adapt to mechanical forces. In particular, we focus on how forces induced by surface contact regulate the physiology of single bacteria and the formation of biofilms. To reach this goal, we employ a multidisciplinary approach that combines concepts and methodologies from microbiology engineering and physics. Our team is composed of scientists from many backgrounds, thereby creating a highly collaborative environment which stimulates scientific discovery.
Position Summary
We aim to recruit a talented and motivated Postdoctoral Fellow to decode the molecular mechanisms allowing bacterial pathogens to sense and respond to mechanical stimuli, and to characterize how these play a role in virulence. The project will consist in first identifying physiological changes induced by mechanical stimulation, to to understand the mechanisms of transduction. Identifying these mechanisms could ultimately open opportunities to develop new therapeutic strategies against antibiotic resistant pathogens. The specific project is flexible based on the interests and skills of the applicant.
The project will likely employ diverse microbiology methodologies such as mutagenesis screens, transcriptomics, high-resolution imaging of fluorescent reporter fusions. On the long run, the project may also incorporate new technologies developed by the lab, including iSCAT microscopy, microfluidics and tissue-engineered organoids. Our lab is also supported by the world-class platforms at EPFL, prociding access to state-of-the-art technology and expertise.
The successful applicant will benefit from a competitive salary .
More about working conditions at EPFL: https://www.epfl.ch/about/working/
Qualifications
A backround in Microbiology or Biophysics is recommended, but applicants from other backgrounds seeking to expand their skills in microbiology are welcome to apply.
How to apply
Applicants should send a brief cover letter describing their research achievements and career goals, a CV, and the contact information of three references to [email protected] . The position will remain open until filled.
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