Researcher in Computational biochemistry

Published: 2023-02-24

Uppsala University is a comprehensive research-intensive university with a strong international standing. Our ultimate goal is to conduct education and research of the highest quality and relevance to make a long-term difference in society. Our most important assets are all the individuals whose curiosity and dedication make Uppsala University one of Sweden’s most exciting workplaces. Uppsala University has over 54,000 students, more than 7,500 employees and a turnover of around SEK 8 billion.

Department of Chemistry – BMC conducts research and education in analytical chemistry, biochemistry, and organic chemistry. More than 100 people work in the department. New employees and students are recruited from all over the world and English is the main working language. The department is located at the Biomedical Centre in Uppsala, which facilitates collaborations with research groups in biology, pharmacy, medicine, and SciLifeLab and gives access to advanced infrastructure for experimental and theoretical studies. You can find more information about us here .

We offer a stimulating, friendly, and interdisciplinary work environment, excellent working conditions, frontier research projects in computational biochemistry, and the opportunity to contribute with and develop your ideas.

We are working in international teams and flexible working hours and home office options, adequate remuneration.

We are an international and interdisciplinary team of dedicated scientists who come from different backgrounds to study biochemical problems such as enzyme evolution, and structure-function-dynamics relationships in biomolecular systems, as well as fundamental problems in physical organic chemistry, using a range of advanced computational tools. Where relevant to solving problems of interest to us, we also engage in methodology development. The work is centered on the use of computational tools to understand and guide the evolution of new enzyme functions, with a particular focus on biocatalytic applications.

More details about the project will be disclosed upon request.

If you want to read more about the group, click here: https://kamerlinlab.com

Read more about our benefits and what it is like to work at Uppsala University

Duties
The position is full-time research. From a scientific perspective, this position will involve computational integration of simulation and experimental data using a range of molecular simulation tools, including both conventional and enhanced molecular dynamics simulations, empirical valence bond, and simulations using either machine learning or statistical analysis, clustering, and dimensionality reduction. It will also include travel to conferences, project meetings with collaborators, and participation in outreach project activities. You are encouraged to take responsibility for the execution of your project and to contribute creatively to our team’s research program.

Requirements
To qualify for employment as a researcher you must have a Ph.D. degree or a foreign degree equivalent to a Ph.D. degree in STEM or a foreign degree equivalent to a Ph.D. degree in STEM. The degree must be obtained at the time of the employment decision. Those who have obtained a Ph.D. degree three years before the application deadline are primarily considered for employment. Additional working experience in the field of computational biochemistry and machine learning to study molecular interactions and protein conformational changes.

The successful candidate is required to have technical expertise in at least one of the following areas:

(1) experience in modeling enzyme reaction mechanisms and/or enzyme function-dynamics relationships, or (2) experience in using enhanced sampling approaches (such as replica exchange or metadynamics) to study biomolecular systems, with particular preference given to studies of the role of conformational dynamics in enzyme engineering or evolution, or (3) experience in programming, using Python, Unix/shell scripting, SQL, Git, HTML, as well as handle pre- and post-processing as well as the visualization of the results.

Moreover, we attach great importance to personal qualities such as creativity, enthusiasm, flexibility, and a positive attitude to work in a team. The applicant will be responsible for a part of a large and challenging project, and the ability to work independently and take responsibility will be required.

Candidates must be able to express themselves very well in spoken as well as written English.

Additional qualifications
Note that attention will be paid to not just overall scientific achievements, but scientific achievements relative to career stage and years of research experience.

All qualifying requirements will be assessed by interview and personal references.

About the employment
The employment is a permanent position, probationary period may be applied. Scope of employment 100 %. Starting date 01-05-2023 or as agreed. Placement: Uppsala

For further information about the position, please contact: Lynn Kamerlin
Email: [email protected], Telephone: +4618-471 4423, +46-70 4250181.

Please submit your application by 10 March 2023, UFV-PA 2023/741.

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Submit your application through Uppsala University's recruitment system.

Placement: Department of Chemistry - BMC

Type of employment: Full time , Permanent position

Pay: Individual salary

Number of positions: 1

Working hours: 100%

Town: Uppsala

County: Uppsala län

Country: Sweden

Union representative: Seko Universitetsklubben [email protected]
ST/TCO [email protected]
Saco-rådet [email protected]

Number of reference: UFV-PA 2023/741

Last application date: 2023-03-10

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