Postdoctoral position in mast cell biology with a focus on their role in gastrointestinal diseases

Updated: about 1 month ago
Deadline: 08 Jul 2022

Do you want to contribute to top quality medical research?

The Department of Medicine, Solna, is one of the largest departments at Karolinska Institutet. The department consists of several units that are separated into different research groups. The core activities of the department are research, doctoral education and undergraduate education for medical and biomedical students. The research has three main profiles: allergy, cardiovascular medicine and inflammatory diseases.


Division

A position is now open in Professor Gunnar Nilsson’s group to investigate mast cells in the gastrointestinal tract and their function in systemic mastocytosis and other inflammatory gastrointestinal disorders.Mast cell activation diseases include several disorders, e.g., mastocytosis and anaphylaxis, where mast cells are activated and their mediators causes a variety of symptoms. The research group on Mast Cell Biology belongs to the Division of Immunology and Allergy. The research within the division is focused on different aspects of immunology and inflammation and is performed in an interdisciplinary setting with strong collaborations with clinical departments and other national and international research groups. 


Your mission

A position is now open in Professor Gunnar Nilsson’s group to investigate mast cells in the gastrointestinal tract and their function in systemic mastocytosis and other inflammatory gastrointestinal disorders. We are seeking a highly motivated and enthusiastic person with a strong background in biology/immunology, with research experience from gastrointestinal diseases, to work within a larger research project with the overall objective to study the mechanisms of mast cells and how they contribute to the symptoms related the gastrointestinal tract. In this part of the project we are investigating mast cell (hyper)reactivity with the aim to identify mechanisms dysregulated in these diseases, interactions between mast cells and other cells, investigations of the microbiota and its effect on mast cells, and to identify biomarkers to be used for diagnostic and/or prognostic purposes. The project involve both national and international collaborations.


Your profile

It is required for the successful candidate to have previous practical research experience from the inflammatory field, including investigations of the microbiota, with knowledge about various in vitro and/or in vivo methods. Experience of mast cell biology and bioinformatics and/or biostatistics is a great advantage. Knowledge in basic immunology is a requirement.

Applicants need to have a strong competence in running projects independently but also having good abilities for team work and cooperation within a dynamic group of scientists with broad expertise and from different nationalities. Proven ability to write scientific articles and present results orally is required. Since the group has many international collaborations excellent communication skills in English are needed.

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director or equivalent.


What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.


Location

The position is located within the Department of Medicine, Solna. The department consists of twelve divisions and each division consists of several research groups. The position is located within he Mast cell group, division of immunology and allergy. https://ki.se/en/meds/gunnar-nilsson-group. The group is currently located in Bioclinicum, the research building at the Karolinska University Hospital in Solna.


Application

An employment application must contain the following documents in English or Swedish:

A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work A complete list of publications A summary of current work (no more than one page)

The application is to be submitted through the Varbi recruitment system.


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