Single Cell Genomics - Specialised Technician

The Institute

The Centro Nacional de Análisis Genómico (CNAG-CRG) is one of the largest Genome Sequencing Centers in Europe. CNAG-CRG researchers participate in major International Genomic Initiatives such as the International Cancer Genome Consortium (ICGC), the International Human Epigenome Consortium (IHEC), the International Rare Diseases Research Consortium (IRDiRC) and the European Infrastructure for life-science information (ELIXIR), as well as in several EU-funded projects. 

It is integrated with the Centre for Genomic Regulation (CRG),an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed by an interdisciplinary, motivated and creative scientific team which is supported both by a flexible and efficient administration and by high-end and innovative technologies. 

In April 2021, the Centre for Genomic Regulation (CRG) received the renewal of the 'HR Excellence in Research ' logo from the European Commission. This is a recognition of the Institute's commitment to developing an HR Strategy for Researchers, designed to bring the practices and procedures in line with the principles of theEuropean Charter for Researchers and theCode of Conduct for the Recruitment of Researchers (Charter and Code). 

Please, check out our Recruitment Policy

The role

The candidate will be integrated in the Single Cell Genomics Team, a highly collaborative, international work environment with well-experienced colleagues in single-cell data production and analysis. She/he will be involved in the development, implementation and execution of single-cell and spatial sequencing applications. The candidate will be responsible to coordinate large-scale, single-cell and spatial project production, including sample biobanking, data generation and documentation. She/he will also be involved in collaborative efforts with our research and clinical partners and diverse production efforts of healthy and diseased human/mouse tissues. We are looking for a highly motivated and creative thinking individual who is interested in working in an environment where the technical sophistication of single-cell and spatial analysis meets innovative approaches for interpreting data and generating new knowledge. We encourage and prioritize applications from under-represented minority groups.  

Specific tasks:

• Execution and coordinating of large-scale data generation.  

• Testing and implementation of novel single-cell and spatial technologies. 

• Automation of single-cell production processes.

About the team

The Single Cell Genomics Team at the CNAG-CRG is dedicated to advance genome research of single cells. The mission of the group is the implementation of latest single-cell and spatial sequencing technologies and their application in a research and translational contexts. The group focuses on the systematic integration of transcriptional and epigenetic data from individual cells to elucidate causalities underlying phenotype formation in health and disease. We successfully established protocols to quantify gene expression and open chromatin of hundred-thousands of isolated single cells (10x Chromium X, 10x Chromium Connect, MissioBio Tapetri, etc) or in tissues (Nanostring CosMx, BGI Stereo-seq, 10x Visium). Our newly developed computational pipelines include methods to deconvolute tissue composition and to track transcriptional dynamics. Our international team joins computational, technical and biological knowledge in order to promote creative thinking while establishing best practices in single-cell and spatial research.  

The group combines collaborative research, development activities and follows research lines on the generation of human cell atlases and immuno-oncology. We are member of the Human Cell Atlas Project and the LifeTime Initiative. 

Web: http://www.cnag.cat/teams/genome-research-unit/single-cell-genomics-team

Whom would we like to hire?  

Professional experience

Must Have

• Strong expertise in single-cell and spatial genomics techniques 

• Trained in next-generation sequencing library preparation 

• More than 10 years of experience as laboratory technician 

• Experience with large-scale project coordination

Languages

• You are fluent in English  

Competences

• Good problem solving, organizational and time management skills

• Strong commitment to high-quality work and sound administrative abilities

The Offer – Working Conditions  

• Contract duration: 3 years 

• Estimated annual gross salary: Salary is commensurate with qualifications and consistent with our pay scales. 

• Target start date: 15/05/2023 

We provide a highly stimulating environment with state-of-the-art infrastructures, and unique professional career development opportunities. To check out our training and development portfolio, please visit our website in the training section .

We offer and promote a diverse and inclusive environment and welcomes applicants regardless of age, disability, gender, nationality, ethnicity, religion, sexual orientation or gender identity.

The CRG is committed to reconcile a work and family life of its employees and are offering extended vacation period and the possibility to benefit from flexible working hours.

Application Procedure

All applications must include:

All applications must be addressed to Dr. Holger Heyn and be submitted online on the CRG Career site - http://www.crg.eu/en/content/careers/job-opportunities   

Selection Process

• Pre-selection: The pre-selection process will be based on qualifications and expertise reflected on the candidates CVs. It will be merit-based. 

• Interview: Preselected candidates will be interviewed by the Hiring Manager of the position and a selection panel if required. 

• Offer Letter: Once the successful candidate is identified the People department will send a Job Offer, specifying the start day, salary, working conditions, among other important details.  

Deadline: Please submit your application by May 14th, 2023 

Suggestions: The CRG believes in ongoing improvement and promotes a culture of feedback. This is one of the reasons we have in place, at your disposal as a candidate, a mechanism to gather your suggestions/complaints concerning your candidate experience in our recruitment processes. Your feedback really matters to us in our aim at creating a positive candidate journey. You can make a difference and help us improve by letting us know your suggestions through the following form. https://recruitment.crg.eu/webforms/recruitment-contact-form-suggestionscomplaints