Research Fellow (Mechanobiology Institute)

The Mechanobiology Institute (MBI), National University of Singapore is a Research Centre of Excellence dedicated to interrogating biological systems from a physical and mechanical perspective. We are a multidisciplinary institute committed to developing new paradigms for biomedical research by focusing on the quantitative analysis of dynamic functional processes. 

We are currently seeking a highly motivated postdoctoral fellow to join Dr. Yan Jie’s and Dr. Alexander Ludwig’s group to work on mechanotransduction mechanisms in polarized epithelial cells. This is a highly collaborative project involving three PIs at MBI as well as the group of Alexander Ludwig at the School of Biological Sciences (SBS), NTU Singapore. The aim of this project is to understand the molecular and cellular mechanisms that sense and transmit mechanical forces from the apical surface of epithelial cells to the Hippo/YAP signalling pathway. A combination of in vitro force measurements, biochemical approaches, cell-based assays and live cell fluorescence imaging of mechanically perturbed cell monolayers will be used to tackle this question. The project and the position will begin in April 2024.

The selected candidate will have the opportunity to work in a world-class research institute with access to a highly interdisciplinary team of biologists, physicists and engineers in Singapore. 

The selected candidate will:

• design, conduct, and analyse experiments at a high scientific standard
• present their data in regular joint group meetings of the participating PIs and their groups
• present their data at local and international meetings and conferences
• supervise and guide PhD students on their projects

• PhD in Biology, Physics, Chemistry or related fields, with a proven track record in publishing
• A strong background in cell biology and molecular biology
• Experience in fluorescence microscopy, biochemistry and/or biophysics would be advantageous
• Excellent verbal and written communication skills and ability to work well in an interdisciplinary and international team
• Highly motivated and independent
• Excellent problem-solving skills and management skills

Location: Kent Ridge Campus

Organization: Mechanobiology Institute

Department : Research

Employee Referral Eligible: No

Job requisition ID : 23465