Job Description
A postdoctoral position is available immediately in Prof. Yoshiaki Ito’s lab. The successful candidate will study one of the following on-going projects.
It is widely accepted that cancer originates from aberrant regulation of tissue stem cells. However, studies of tissue stem cells in many organs are still at early stages. There are two types of stem cells in stomach: rapidly proliferating stem cells (Isthmus stem cells) and dormant stem cells, a subpopulation of terminally differentiated chief cells at the gland base. Isthmus stem cells are responsible for generating all cell types in the stomach under the homeostatic conditions. We recently identified cytoskeletal scaffold protein, IQGAP3, as a highly specific isthmus stem cell factor during homeostasis (GUT, 2020). We further found that upon tissue damage, IQGAP3 was robustly induced in dormant stem cells, which acquired proliferating capacity to engage in tissue repair. The objective is detailed molecular characterization of these two types of stem cells.
Qualifications
We seek a highly motivated and innovative postdoctoral fellow with the ability to work independently and as part of a team. Candidates should have PhD and/or MD degree with a strong background in molecular biology, biochemistry and cell biology. Prior experience with using mouse models to study cancer and 1-2 years of postdoctoral experience in these areas are required.
Applications should include full curriculum vitae, publication list, information on years of experience in research and laboratory work, and names and contact information (email and telephone numbers) of 2 referees. Please also include a summary of your research experience.
Covid-19 Message
At NUS, the health and safety of our staff and students are one of our utmost priorities, and COVID-vaccination supports our commitment to ensure the safety of our community and to make NUS as safe and welcoming as possible. Many of our roles require a significant amount of physical interactions with students/staff/public members. Even for job roles that may be performed remotely, there will be instances where on-campus presence is required.
Taking into consideration the health and well-being of our staff and students and to better protect everyone in the campus, applicants are strongly encouraged to have themselves fully COVID-19 vaccinated to secure successful employment with NUS.
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