PhD Research Fellow in Plant Reproduction and Developmental Biology (ref 257250)

8 Feb 2024
Job Information

Organisation/Company

University of Oslo

Research Field

Biological sciences

Researcher Profile

First Stage Researcher (R1)

Country

Norway

Application Deadline

29 Feb 2024 - 23:00 (Europe/Oslo)

Type of Contract

Temporary

Job Status

Full-time

Hours Per Week

37.5

Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

Genomic imprinting is an epigenetic phenomenon giving rise to parent-of-origin allele specific expression that occurs mainly in placental tissue/endosperm in animals and plants and is hypothesized to be involved in the allocation of nutrient resources to the growing embryo. Although imprinting has evolved independently in plant and animal lineages, similar epigenetic mechanisms, including DNA methylation, histone tail modification, and sRNA-guided silencing mechanisms are conserved. In plants, genomic imprinting is hypothesized to be established in the gametes and reflected in parent-of-origin allele specific expression in the endosperm after fertilization [Hornslien et al. Plant Physiol. 2019]. 

Using temporal and spatial endosperm specific GFP markers and fluorescence-assisted nuclear sorting to study endosperm expression by allele-specific transcript profiling, we have shown that imprinting patterns can be established late in endosperm development and in specific domains, challenging the current hypothesis [van Ekelenburg et al. Plant Physiol. 2023]. These findings are supported by experimental evidence from hybridization crosses between different Arabidopsis species: Here, a parental-specific expression can be reversed by fertilization by a different species, suggesting a dynamic regulation mechanism that can act after fertilization [Bjerkan et al., Plant J. 2020]. We have established that using different species in hybrid crosses leads to diametrically opposite phenotypic consequences in the endosperm, thus allowing association of imprinting patterns to a phenotype [Bjerkan et al., Front. Plant Sci. 2023].

For more information and how to apply: https://www.jobbnorge.no/en/available-jobs/job/257250/phd-research-fellow-in-plant-reproduction-and-developmental-biology

Requirements

Research Field

Biological sciences

Education Level

Master Degree or equivalent

Additional Information
Work Location(s)

Number of offers available

1

Company/Institute

Department of Bio

Country

Norway

Geofield

Where to apply

Website

https://www.jobbnorge.no/en/available-jobs/job/257250/phd-research-fellow-in-pl…

Contact

City

Oslo

Website

https://www.mn.uio.no/ibv/english/

Street

PO box 1072 Blindern

Postal Code

NO-0316

E-Mail

[email protected]

STATUS: EXPIRED