LC/MS laboratory manager (Triple Quadrupole)

Updated: about 1 month ago
Deadline: 13 Dec 2021

Department

With more than 1,000 employees, including 135 pioneering principal investigators, as well as a population of about 3,400 passionate students, the Faculty of Applied Sciences is an inspiring scientific ecosystem. Focusing on key enabling technologies, such as quantum- and nanotechnology, photonics, biotechnology, synthetic biology and materials for energy storage and conversion, our faculty aims to provide solutions to important problems of the 21st century. To that end, we train students in broad Bachelor's and specialist Master's programmes with a strong research component. Our scientists conduct ground-breaking fundamental and applied research in the fields of Life and Health Science & Technology, Nanoscience, Chemical Engineering, Radiation Science & Technology, and Engineering Physics. We are also training the next generation of high school teachers and science communicators.

The Department of Bionanoscience focuses on the fundamental understanding of biological processes, from the level of single molecules to the full complexity of living cells. This research provides fascinating insight in the molecular mechanisms that lead to cellular function. Furthermore it enables the in vitro bottom-up construction of cellular machinery and it impacts applications ranging from biomolecular diagnostics to novel antibiotics and targeted nanomedicine. The department features a strongly multidisciplinary and international team of scientists, whose research areas include single-molecule biophysics, synthetic biology, as well as (quantitative) cell biology.

Researchers within the Department use LC/MS for applications ranging from engineering antibiotic synthesis in bacteria (described here: https://www.nature.com/articles/s41589-018-0084-6 ) to building artificial life (https://www.nature.com/articles/s41467-020-17863-5 ). One of our novel LCMS methods that combines features of targeted proteomics with metabolomics is described here: pubmed.ncbi.nlm.nih.gov/27595277 . This method was used to discover control points in a metabolic pathway (described here: journals.asm.org/doi/10.1128/mBio.02703-19 ).


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