Post-doctoral researcher: Personalized Medicine Acceleration through Rapid Omics Profiling

25 Jan 2024
Job Information

Organisation/Company

Luxembourg Institute of Health

Department

Ressources Humaines

Research Field

Biological sciences » Other

Researcher Profile

Recognised Researcher (R2)

Country

Luxembourg

Application Deadline

29 Feb 2024 - 12:00 (Europe/Luxembourg)

Type of Contract

Temporary

Job Status

Full-time

Hours Per Week

40

Offer Starting Date

1 Mar 2024

Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

The Multi-omics Data Science Group is part of the Department of Cancer Research at LIH. We focus on various modalities of high-throughput molecular data obtained in cancer biology. We aim to integrate corresponding data layers to improve our understanding of cancers and drive better patient stratification and treatment. Dr. Reka Toth, the PI of the project,  has expertise in epigenetics, bioinformatics and multi-omics profiling.

PROJECT

We are looking for a proactive, agile and committed postdoctoral researcher to join our new project aiming to develop techniques for rapid omics profiling.
Recent studies have uncovered biomarkers at various omics levels. Nonetheless, a substantial limitation of these biomarkers is the time-consuming aspects of sample processing, data acquisition and analysis, and the demand for specialized expertise. A pivotal advancement in translational efforts would require streamlining and enhancing this process. The goal of our project is to establish fast, reliable methods to exploit the recent technological and scientific advances to improve personalized medicine. Therefore, we would like to establish a platform that allows clinicians to get timely results from previously developed multi-omics biomarker panels based on Nanopore barcode sequencing and targeted proteomics. We also aim to establish a cfDNA-based DNA and methylome sequencing method to monitor cancer patients and identify potential relapse before it is possible with traditional imaging methods.
The project is primarily centered around wet-lab activities with added computational components. The level of involvement in the computational aspect is adaptable to suit the candidate's preferences. As part of our team, we offer a vibrant multidisciplinary and multinational working environment, fostering collaboration and innovation. LIH offers comprehensive training programs in both scientific advancements and essential soft skills.
 

Scientific contacts

Dr. Reka Toth  ([email protected] )
 

KEY ACCOUNTABILITIES

• Set up the project, manage sample processing
• Conduct wet-lab experiments, optimize biomarker analysis, run cfDNA isolation and sequencing
• Participate in data analysis and model generation – depending on individual agreement
• Publish results in scientific journals and/or file patents if applicable
• Participate in training and international scientific conferences
• Disseminate results to the scientific community and the public
• Participate in laboratory activities including seminars and interaction with other teams

KEY SKILLS, EXPERIENCE AND QUALIFICATIONS

• PhD in molecular/cellular biology/biochemistry or similar, with solid research experience.
• Wet laboratory and analytical skills, experience with next-generation or long-read sequencing.
• Interest in bioinformatics and programming
• Previous experience in bioinformatics, R and/or Python programming will be considered a strong asset
• Scientific creativity and originality, precise perseverance, writing skills, good communication skills
• Language skills: fluent command of English; knowledge of other languages of the European Union is an asset

IN SHORT

• Contract type:           2-year fixed-term contract
• Work hours:               Full time
• Location:                    Strassen
• Start date:                 ASAP
• Ref:                             MC/PDPMAROP0124/RT/MODAS

HOW TO APPLY

Applications including a cover letter, a  curriculum vitae and reference letters should be sent through our website via the apply button below. Please apply ONLINE formally through this web page. Applications by email will not be considered.

All interested candidates irrespective of age, gender, race, disability, religion or ethnic background are encouraged to apply.
 

GENDER EQUALITY

The LIH is an equal opportunities employer.
We are fully committed to removing any discriminatory barrier related to gender, and not only, in recruitment and career progression of our staff.The LIH is attentive to gender representation among its leadership staff and aims to eliminate obstacles to the recruitment and promotion of female leaders and their career development.

 

Requirements

Research Field

Biological sciences » Other

Education Level

PhD or equivalent

Skills/Qualifications

• PhD in molecular/cellular biology/biochemistry or similar, with solid research experience.
• Wet laboratory and analytical skills, experience with next-generation or long-read sequencing.
• Interest in bioinformatics and programming
• Previous experience in bioinformatics, R and/or Python programming will be considered a strong asset
• Scientific creativity and originality, precise perseverance, writing skills, good communication skills
• Language skills: fluent command of English; knowledge of other languages of the European Union is an asset

Languages

ENGLISH

Level

Excellent

Additional Information
Work Location(s)

Number of offers available

1

Company/Institute

Luxembourg Institute of Health

Country

Luxembourg

Geofield

Where to apply

Website

https://careers.lih.lu/jobs/detail/post-doctoral-researcher-personalized-medici…

Contact

State/Province

Strassen

City

Strassen

Website

http://www.lih.lu

Street

1A-B, rue Thomas EdisonL-1445 StrassenLuxembourg

Postal Code

1445

STATUS: EXPIRED