Skin cells communication through melanin exchange under physiological and inflammatory conditions

Updated: 3 months ago
Job Type: FullTime
Deadline: 15 Sep 2026

19 Jun 2026
Job Information
Organisation/Company

INSERM
Department

U1151
Research Field

Biological sciences » Biology
Researcher Profile

Recognised Researcher (R2)
Positions

Postdoc Positions
Application Deadline

15 Sep 2026 - 00:00 (Europe/Paris)
Country

France
Type of Contract

Temporary
Job Status

Full-time
Hours Per Week

35
Offer Starting Date

1 Jan 2027
Is the job funded through the EU Research Framework Programme?

Not funded by a EU programme
Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

We are looking for an enthusiastic researcher to study how skin cells communicate through the exchange of pigment particles under physiological and inflammatory conditions. Our recent work described that secreted melanin particles are decorated by extracellular vesicles (Benito-Martínez, Salavessa, et al. Nat Cell Biol. 2026), suggesting a previously unrecognized potential for melanin-mediated intercellular communication in human skin. The project aims to uncover how inflammation rewires the signaling properties of melanin particles and alters pigment fate in skin cells, revealing new mechanisms underlying pigmentary disorders. The project will combine cell and molecular biology, advanced imaging approaches, transcriptomics, flow cytometry and 2D/3D human skin models.


Where to apply
E-mail

[email protected]

Requirements
Research Field
Biological sciences » Biology
Education Level
PhD or equivalent

Skills/Qualifications

Candidates with a PhD in molecular and cellular biology, obtained during the past four years, and with experience in membrane dynamics, extracellular vesicle biology, organelle biology, advanced microscopy, and/or 3D model systems are encouraged to apply. 


Specific Requirements

We are seeking a curious and creative researcher with strong communication skills in English, who enjoys working on exploratory projects and contributes to a collaborative, interdisciplinary, open and friendly research environment.


Languages
ENGLISH
Level
Excellent

Research Field
Biological sciences » Biology
Years of Research Experience
4 - 10

Internal Application form(s) needed
Job-ad_INEM_LEO_Membramics-1.pdf
English
(341.86 KB - PDF)
Download
Additional Information
Benefits

The host laboratory, Cellular & Membrane Dynamics in Stress Response (MEMBRAMICS), directed by Etienne Morel, is part of the Institut Necker Enfants Malades (INEM) in Paris. The team’s research focuses on how mammalian cells exploit membrane dynamics and organelle biology to adapt to various stress scenarios and external cues, including nutrient fluctuations, mechanical forces, infection, UV exposure and inflammation. INEM is a leading biomedical research institute supported by INSERM, CNRS and Université Paris Cité, and located on the Necker campus alongside the Necker-Enfants Malades Hospital and the Imagine Institute. Researchers benefit from access to state-of-the-art core facilities, including imaging, genomics, histology, flow cytometry, bioinformatics and proteomics platforms.


Eligibility criteria

Candidates with a PhD in molecular and cellular biology, obtained during the past four years.


Selection process

Applications will be accepted through early September 2026.
Interviews with selected candidates will conclude in mid-October 2026.
The candidate will be selected in early November 2026.
The position will begin no earlier than January 2027.


Website for additional job details

https://www.institut-necker-enfants-malades.fr/en-gb/equipe/membramics-cellular…

Work Location(s)
Number of offers available
1
Company/Institute
Institut Necker Enfants Malades (INEM, INSERM U1151/CNRS8253)
Country
France
City
PARIS
Postal Code
75015
Street
160 RUE DE VAUGIRARD
Geofield


Contact
City

Paris
Website

https://www.institut-necker-enfants-malades.fr/en-gb/equipe/membramics-cellular-membrane-dynamics-stress-response
https://www.inserm.fr/
Street

160 rue de Vaugirard
Postal Code

75015
E-Mail

[email protected]
[email protected]

STATUS: EXPIRED

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