Postdoc positions (experimental or computational) in normal and malignant hematopoietic stem cell biology

Updated: over 1 year ago
Deadline: 14 Aug 2022

The Porse group at University of Copenhagen is seeking two highly motivated postdocs to work on stem cell biology.

Our research/The group
The Porse group (Finsen Laboratory/BRIC) has a diverse and stimulating environment and we focus our research on elucidating mechanisms governing normal and malignant haematopoiesis with special emphasis on the behaviour of hematopoietic stem cells (HSCs) during adult haematopoiesis and leukemic stem cells (LSCs) in acute myeloid leukaemia. To this end, we employ mouse models of human AML, mouse knockout lines of putative HSC/LSC regulators, primary patient material and a broad range of genome-wide approaches and single cell analyses incl. cutting edge single cell proteomics.

The Porse group is affiliated with the Finsen Laboratory at Rigshospitalet as well as with BRIC at the University of Copenhagen. You can read mor about Porse group here: https://www.bric.ku.dk/research-groups/Research/Porse_Group/

The research projects
Two projects are available for the successful applicants:

  • Characterization and targeting of VEXAS, a recently discovered hematological syndrome
  • Computational analysis of state-of-the-art single cell proteomics data derived from normal individuals and patient with hematological malignancies

  • Starting date: As soon as possible, exact date after agreement
    Duration: Initially for two years
    Hours per week: 37 hours

    Qualifications
    We expect you to be a highly motivated and highly ambitious scientist with the following qualifications:

    • A PhD in life sciences or equivalent research experience
    • For the wet lab project we are looking for candidates with strong documented research experience and expertise in either single-cell technologies, experimental mouse work, biochemistry, advanced flow cytometry, genome-wide approaches (ChIP-seq, Chromatin Conformation Capture, etc) or functional haematopoiesis.
    • For the computational project, we are looking for candidates with strong documented research experience and expertise in the analysis of sc-omics data and/or proteomics data.
    • Candidates with combined experiences are particularly encouraged to apply-
    • Good organizational skills and a detail-oriented structured approach to work tasks
    • Collaborative skills
    • Excellent English skills written and spoken.


    Place of employment
    The employment is at BRIC, University of Copenhagen. BRIC is located in the Biocenter, close to the centre of Copenhagen. We offer creative and stimulating working conditions in a dynamic and international research environment. Our research facilities include modern laboratories and a number of core facilities shared between the 20 research groups at BRIC and the neighboring Finsen Laboratory. We have weekly journal clubs, data clubs, seminars with invited speakers and a young researchers club ASAP, our own PhD programme, MoMeD and our own Postdoc Career Programme.

    Please read more about BRIC on https://www.bric.ku.dk/

    Terms of employment
    The average weekly working hours are 37 hours per week. 
    The 2 postdoc positions are fixed-term positions for two years. The starting date is as soon as possible after agreement.

    Salary, pension and other conditions of employment are set in accordance with the Agreement between the Ministry of Finance and AC (Danish Confederation of Professional Associations) or other relevant organisations. Currently, the monthly salary starts at 35,600 DKK/approx. 4,780 EUR (April 2022 level). Depending on qualifications, a supplement may be negotiated. The employer will pay an additional 17.1 % to your pension fund.

    Foreign and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.

    The position is covered by the Job Structure for Academic Staff at Universities 2020.

    Questions
    For further information regarding the position, please contact Prof. Bo Porse; [email protected] .
    Foreign applicants may find this link useful: www.ism.ku.dk  (International Staff Mobility).

    Application procedure
    Your online application must be submitted in English by clicking ‘Apply now’ below. Furthermore, your application must include the following documents/attachments – all in PDF format:

  • Motivated letter of application (max. one page).
  • CV incl. education, work/research experience, language skills and other skills relevant for the position.
  • A certified/signed copy of a) PhD certificate and b) Master of Science certificate. If the PhD is not completed, a written statement from the supervisor will do.
  • List of publications.

  • Deadline for applications: 14 August 2022, 23.59pm CET
    We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

    The further process
    After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

    You can read about the recruitment process at https://employment.ku.dk/faculty/recruitment-process/

    The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

    The University of Copenhagen wish to reflect the diversity of society and encourage all qualified candidates to apply regardless of personal background.


    Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.



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