Postdoc in Molecular Biology for Gene Delivery Project

DTU Health Tech is looking for an experienced and highly motivated industrially-oriented Postdoc to join our growing BioInnovation Institute (BII) project team developing a novel platform technology for enhancing gene therapy.

The job
We are developing technologies for improved and physiologically adapted gene transfection. Led by PI Professor Thomas L. Andresen, our team’s initial focus is to generate a transfection system for immune activating cytokines that can stimulate immunologic elimination of solid cancers. We believe our technology holds the potential to expand in to other disease areas as our project progresses. The ultimate goal is to generate the technological foundation for a new biotech start-up.

The successful candidate will support the design, implementation, analysis and interpretation of transfection studies. The candidate will contribute to the performance of and the analysis of the transfection systems, mostly in vivo, using flowcytometry, ELISA and other immunoassays.

The successful candidate will have an immediate impact on the team and begin contributing to the project on day one. This position holds a unique opportunity to drive important activities in order to meet critical project milestones, as well as access to outstanding scientific platforms at both DTU and BII. This is a complex project running in a team-oriented environment where efficiency and communication are vital.  

Responsibilities:

• Therapeutic evaluation studies in experimental models
• Post-transfection tissue analysis using various immunoassays
• Provide input in evaluation of in vitro transfection efficiency in cell cultures
• Participate in gene target identification, design and optimization
• Contribute to documentation and communication of obtained results 

Our expectations of you
You must hold a PhD degree (or equivalent) ideally in biology, biochemistry, medicine, veterinary medicine, pharmaceutical or biological science.

Preferable qualifications:

• FELASA certification (mandatory)
• Experience handling experimental animals
• Experience with immunoassays (e.g., flowcyometry, PCR, ELISA, IHC)
• Experience with transfection and gene engineering/editing
• Experience with cell assays and flow cytometry analysis
• Experience with cell culture and mouse cancer models
• Knowledge of relevant biological targets for cancer therapy is an advantage
• Knowledge of additional disease areas is an advantage

We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.

Salary and appointment terms
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union. The position is for one year starting February 2022 (or according to mutual agreement).

You can read more about career paths at DTU here .

Further information
Further information may be obtained from Project coordinator Ashley Montgomery, +45 3164 2424.

You can read more about DTU Health Tech at www.healthtech.dtu.dk/english . 

If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark . 

Application procedure
Your complete online application must be submitted no later than15 January 2022 (Danish time).Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply online", fill out the online application form, and attach all your materials in English in one PDF file. The file must include:

• Application (cover letter)
• CV
• Academic Diplomas (MSc/PhD)
• List of publications

Applications received after the deadline will not be considered.

All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply.

DTU Health Tech
DTU Health Tech engages in research, education, and innovation base on technical and natural science for the healthcare sector. The Healthcare sector is a globally expanding market with demands for the most advanced technological solutions. DTU Health Tech creates the foundation for companies to develop new and innovative services and products which benefit people and create value for society. DTU Health Techs expertise spans from imaging and biosensor techniques, across digital health and biological modelling, to biopharma technologies. The department has a scientific staff of about 210 persons, 130 PhD students and a technical/administrative support staff of about 160 persons, of which a large majority contributes to our research infrastructure and related commercial activities.

Technology for people
DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear vision to develop and create value using science and engineering to benefit society. That vision lives on today. DTU has 12,900 students and 6,000 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. DTU has campuses in all parts of Denmark and in Greenland, and we collaborate with the best universities around the world.