Development of nanomedicine to combat melanomas

8 Feb 2024
Job Information

Organisation/Company

Université Libre de Bruxelles

Research Field

Biological sciences » Biological engineering
Biological sciences » Biology
Medical sciences

Researcher Profile

Recognised Researcher (R2)
Leading Researcher (R4)
First Stage Researcher (R1)
Established Researcher (R3)

Country

Belgium

Application Deadline

6 Mar 2024 - 22:00 (UTC)

Type of Contract

Temporary

Job Status

Full-time

Offer Starting Date

1 Mar 2024

Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

Summary of the project

While new therapeutic advances have greatly improved the prognosis of patients with high-risk or even metastatic melanoma, various resistance mechanisms have been identified, prompting researchers to find combinations to counter them. This project aims to develop a specific nanomedicine to be further combined with the first line adjuvant therapies for melanoma. The study aims to reach proof of targeting of the formulation with pharmacokinetic and toxicological profiles’ determination and provide preclinical efficacy data in vivo.

Résumé du projet

Bien que les nouvelles avancées thérapeutiques aient considérablement amélioré le pronostic des patients atteints de mélanome à haut risque ou même métastatique, divers mécanismes de résistance ont été identifiés, incitant les chercheurs à trouver des combinaisons pour les contrer. Ce projet vise à développer un nanomédicament spécifique qui serait associé aux thérapies adjuvantes de première ligne pour le mélanome. L'étude vise à prouver le ciblage de la formulation en déterminant ses profils pharmacocinétique et toxicologique et à fournir des données précliniques sur l'efficacité in vivo.

Funding category: Financement public/privé

PHD title: Doctorat en sciences biomédicales et pharmaceutiques
PHD Country: Belgique

Requirements
Specific Requirements

Background required: master in biology, biomedical sciences, pharmacy, biotechnology, bioengineering. People with PhD diploma ARE NOT eligible.

Skills (preferred; may be acquired during the training): cell culture, cell transfection, molecular biology, PCR, Western blot, Drug delivery

Domain of the research:  experimental oncology, pharmaceutical sciences, molecular biology

Language: fluent French or English is required

Additional Information
Work Location(s)

Number of offers available

1

Company/Institute

Université Libre de Bruxelles

Country

Belgium

City

Bruxelles

Geofield

Where to apply

Website

https://www.abg.asso.fr/fr/candidatOffres/show/id_offre/120021

Contact

Website

https://pharmacie.ulb.be/version-francaise/la-recherche/chercheurs/veronique-mathieu

STATUS: EXPIRED