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Field
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principles that govern antibody function in vivo. Our approaches combine in vivo and in vitro immunology and cell biology with biomechanical assays (e.g., shear force as a variable in antibody–Fc receptor
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approaches. The successful candidate will lead studies of multidrug transporters, including recombinant protein expression and purification, in vitro biochemical and biophysical analyses, and single-particle
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Max Planck Institute of Molecular Physiology, Dortmund | Dortmund, Nordrhein Westfalen | Germany | about 1 month ago
microscopy, in vitro reconstitution of large complexes, membrane proteins, cryogenic electron tomography Proven research track record (publications/preprints) Ability to work independently and collaboratively
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Demonstrated ability to conduct independent research and publish in a peer-reviewed journal. Responsibilities: Lead independent and collaborative research projects Design and execute in vitro and in vivo
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Massachusetts Institute of Technology | Cambridge, Massachusetts | United States | about 1 month ago
people from all backgrounds and at all levels of training. PREFERRED: expertise in high-dimensional flow cytometry, in vitro or in vivo immune models, animal models, human immunology, functional genomics
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analysis. Our laboratory develops physiologically relevant in vitro platforms, including three-dimensional culture systems, tunable hydrogel matrices, microfluidic devices, organ-on-chip models, and
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vitro, ex vivo, and in vivo experiments investigating the microbiota and bacterial extracellular vesicles in anti-tumor immunity and immunotherapy response, with an emphasis on lung cancer, independently
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lab techniques: classical diagnostic parasitology techniques, microscopy, parasite culture, in vitro assays, DNA and RNA extraction, PCR, RTPCR, qPCR, qRT-PCR, digital PCR, and ELISA. Experience with
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mammalian/tumor cell line maintenance (BSL-2), in vitro transmigration, and ex vivo explant cultures. Confocal/fluorescence microscopy, IHC, and ICC. Independent execution of autoimmune and T-cell
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nanoparticles targeted to prostate cancer models by functionalization. Work in vitro using patient-derived prostate cancer biopsies, cell culture experiments including cytotoxicity assays, uptake studies, and