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image-based siRNA screens, we have identified novel regulators of ER-phagy. This project aims to investigate the molecular mechanisms of ER-phagy and how this contributes to cancer progression
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/exosomes. Advanced cell culture, molecular biology and imaging approaches will be combined to study cellular responses and mechanisms relevant to oral disease and regenerative medicine. The overall aim is to
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Oral Tribology to 4D Micro-CT Failure Analysis”. The laboratory-based project combines dental biomaterials, development of wear-testing methods, mechanical characterisation and advanced X-ray imaging
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”. The laboratory-based project combines dental biomaterials, development of wear-testing methods, mechanical characterisation and advanced X-ray imaging, with collaboration in restorative dentistry/prosthodontics
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the project will be the investigation of cellular communication through secretomics analyses, including extracellular vesicles/exosomes. Advanced cell culture, molecular biology and imaging approaches
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of algorithms for medical image analysis. The successful candidate will investigate computational complexity, stability, and numerical summaries of multiparameter persistence, as well as applications to medical
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applications to medical data. The project will combine theoretical work on multiparameter persistence with the design and implementation of algorithms for medical image analysis. The successful candidate will
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progression. Using image-based siRNA screens, we have identified novel regulators of ER-phagy. This project aims to investigate the molecular mechanisms of ER-phagy and how this contributes to cancer
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transcriptomics or proteomics, multiplexed imaging and/or integration of spatial transcriptomics with single-cell RNA-sequencing datasets. Experience from relevant research projects will be considered an advantage
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will be further developed by the successful candidate in collaboration with the supervisory team. Main tasks The successful candidate will: develop and evaluate image-classification workflows