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-sputum whole-genome sequencing within the DiSrupT RR-TB trial. The clinical trial will evaluate a multi-component intervention to reduce the transmission of RR-TB. A key component of the intervention is a
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to identify genetic and genomic features that may convey protection against aging and neurodegeneration. This senior bioinformatics postdoc will be expected to contribute actively to the scientific endeavors in
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-on experience with CRISPR-Cas genome editing, including generation and validation of knockout (KO) lines. Expertise in base- and prime editing, endogenous gene tagging and targeted knock-in of large DNA cargos
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that leverage state-of-the-art AI methods (deep learning, generative AI, Bayesian modelling, active learning, etc.) to combine cellular imaging data, chemical compound structure, viral genomes and other omics