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Field
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focused on accelerating therapy development for leukodystrophies: rare genetic disorders affecting the brain's white matter. The network aims to strengthen the full translational pathway from disease
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have the potential for treating certain genetic diseases and cancer. Co-authors are dr hab. eng. Umesh Kalathiya from the ICCVS, University of Gdańsk and prof. Sławomir Makowiec from the Gdańsk
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experiments using cancer and stromal cell models, including CRISPR/Cas9-based genetic approaches to investigate Cx43-dependent mechanisms. Establish and characterise tumour–stromal co-culture and 3D models
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microbiology and structural biology; experimental design and execution; scientific literature research and data mining; molecular biology/genetic engineering (cloning, subcloning, mutagenesis, construction
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, gender, gender identity or expression, national or ethnic origin, shared ancestry, age, status as an individual with a disability, military or veteran status, genetic information, or other protected
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Host institution: Erasmus University Medical Centre Rotterdam (EMC-a), Department of Molecular Genetics , Rotterdam, Netherlands Supervisor:Dr. Miao-Ping Chien Co-supervisors: Prof. Thierry Voet
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remodelling events, thereby generating the mechanical forces required for its motility. This motility also relies on the dynamics of adhesion structures to the extracellular matrix. Genetic evidence
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mechanistically using an epithelial cell model. This interdisciplinary project provides training in developmental biology, bioinformatics, spatial transcriptomics, cell culture, imaging and molecular genetics
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mechanistically using an epithelial cell model. This interdisciplinary project provides training in developmental biology, bioinformatics, spatial transcriptomics, cell culture, imaging and molecular genetics
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, the interplay between genetic variation and human phenotypes, and the development of AI-driven approaches to better understand human biology and disease and to translate these insights into data-driven strategies