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Massachusetts Institute of Technology (MIT) | Cambridge, Massachusetts | United States | 2 months ago
CRISPRi, pooled genetic screens, or barcoded libraries; flow cytometry, fluorescence-activated cell sorting, or related single-cell measurement approaches; RNA sequencing, proteomics, metabolomics, or other
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carries out experiments using mouse and human brain material, cultured cells, high resolution fluorescence imaging and image analysis, biochemical, as well as molecular biology approaches. Operates and
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to treat cancer and inflammatory diseases. The work will require mastering a broad spectrum of skills from fluorescence microscopy, nanomedicines, biomaterials, immunology, and cancer biology. In addition
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biochemical or molecular assays. Experience with fluorescence-based assay development. Experience with biochemical reconstitution of multi-component protein systems or signaling pathways. Experience with
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: Experience with CRISPRi, pooled genetic screens, or barcoded libraries; flow cytometry, fluorescence-activated cell sorting, or related single-cell measurement approaches; RNA sequencing, proteomics
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behavior, including DLS, Langmuir-Blodgett test. Spectroscopic and chromatographic methods (UV-VIS, fluorescence, HPLC) Maintain detailed records of material preparation conditions for reproducibility. 3
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of written and spoken English. Those with expertise in MRI imaging analysis and neuroscience in clinical population, especially in psychiatry research will be preferred. The appointee will work
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and spatial analysis techniques to large-scale spatial transcriptomics and imaging datasets, using tools such as MuSpAn to identify spatial biomarkers and uncover the biological mechanisms driving
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The performance of X-ray microscopy has improved significantly over the last decade, enabling synchrotron-based X-ray imaging to resolve individual transistors in modern semiconductor devices. As the industry moves
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to define respiratory and motor circuit function using approaches that may include whole-body plethysmography, diaphragm and other muscle EMG, neural electrophysiology, in vivo calcium imaging, viral circuit