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Field
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drugs such as artemisinin, there is an urgent need to develop next generation drugs for malaria. Our laboratory has identified a novel host based phospholipase A2 enzyme, peroxiredoxin 6 (PRDX6-PLA2
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University of North Carolina at Chapel Hill | Chapel Hill, North Carolina | United States | about 1 month ago
. Familiarity with enzyme electrode fabrication, surface modification, and analytical assay development. Strong experimental design, data analysis, communication, and scientific writing skills are required
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, enzyme-loaded, stimuli-responsive or otherwise functionalized polymersomes or liposomes, will be highly valued. Expertise in characterization techniques for soft vesicular materials (such as Optical and
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) enzyme biochemistry and mechanism. Under the direction of faculty leadership, this position will perform laboratory research using protein overexpression, anaerobic protein purification techniques
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Y). She/he will build on the strong expertise of the laboratory on the conception and assembly of molecular programs made out of DNA oligonucleotides and enzymes, and capable of information-processing
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. Making amino acid substitutions and characterizing their consequences. 4. Similarly for the effects of ligand binding. 5. Deposition of enzymes on electrodes and electrochemical characterization of said
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mammalian cell culture, molecular cloning (Gibson, In-Fusion, and restriction enzyme cloning), primer and construct design in SnapGene, site-directed mutagenesis, and molecular knockout. Experience in mass
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somatic hypermutation, when the enzyme activation-induced deaminase (AID) generates DNA double-strand breaks at immunoglobulin genes and major proto-oncogenes such as MYC and BCL6. We have shown that early
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for a Predoctoral Researcher to develop a PhD project on the design and application of enzyme-powered nanomotors for the treatment of osteoarthritis and joint-related diseases. Main tasks and
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) enzyme biochemistry and mechanism. This position will utilize protein overexpression, anaerobic protein purification techniques, and a variety of bioanalytical, spectroscopic, and structural approaches