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Field
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Job Summary/Basic Function: Join the Nagarajan Laboratory as a Postdoctoral Fellow to investigate the molecular basis of enzyme function and contribute to the development of novel antimicrobial
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B cell lymphomas including diffuse large B cell lymphoma and Burkitt lymphoma. They arise as a byproduct of somatic hypermutation, when the enzyme activation-induced deaminase (AID) generates DNA
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and evaluation of pathogen-selective, enzyme-activated carrier chemistry and will work closely with computational collaborators and other team members on iterative design-synthesize-test workflows
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blot analysis, polarography, enzyme assay, and Enzyme-Linked Immunosorbent Assay. The individual will be able to implement the quantitative analytical methods listed and efficiently develop skills
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expected to lead the section of the project in relation to provision of functional prime editors: pegRNA design, novel enzymes and variants, also molecular aspects of detecting edits, to make specific
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bacterial cell counts in a flow cytometer, hydrolytic enzyme activity measurements, and nutrient analysis. The postdoc will also be responsible for data analysis and publication. Duties/Responsibilities
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University of North Carolina at Chapel Hill | Chapel Hill, North Carolina | United States | 19 days ago
biomaterials. Preferred Qualifications, Competencies, and Experience Experience in mammalian cell culture, ELISA (Enzyme-Linked Immunosorbent Assay), small animal models, Flow Cytometry, and ELISpot (Enzyme
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of nuclear xenobiotic receptors, (2) the mechanism of selective modulation of highly homologous drug-metabolizing enzymes. We are taking a hypothesis-driven and technology-enabled multidisciplinary approach
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rodents, flow cytometry acquisition and analysis, immunohistochemistry, fluorescence microscopy, and molecular biology (RNA/protein extraction, RT-PCR, enzyme-linked immune-sorbent assay (ELISA), western
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with disease induction (EAU), adoptive transfers, and genetic fate mapping. DNA/RNA extraction, PCR/qRT-PCR, Western blot, mAb purification, comet assays, and enzyme kinetics/spectroscopy. Sterile