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cell immunology, mucosal immunology, and cancer immunology using animal models and single-cell multiomics/spatial transcriptomics approaches. This postdoctoral researcher will combine wet-lab molecular
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stress affects specific cell types in the nervous system and the gut, using human pluripotent stem cell (hPSC)-derived models of the enteric nervous system. Our work sits at the intersection of stem cell
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cellular biology approaches. The Park Lab develops human stem cell-based neural models to investigate molecular and cellular mechanisms regulating neurodevelopment and neural function, and to understand how
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laboratory (http://www.garglab.org ) uses approaches from genomics, molecular biology, systems biology, and data science to understand cellular heterogeneity. We want to understand how cell systems with
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single-cell genomics. Responsibilities: Design and run lineage-tracing and tumor-initiation experiments in genetically engineered mouse models of lung injury and adenocarcinoma Generate and help analyze
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experience with mammalian cell culture, rigorous experimental design, and standard wet lab techniques is expected. Experience with basic wet lab techniques, pre-clinical animal models (PDX), ctDNA assays
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and cellular mechanisms underlying these disorders using cell-based assays, blood vessel organoids, and zebrafish and mouse models, working alongside neurosurgeons, computational scientists, and
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-yale/benefits-summary Salary For this appointment will be no less than $68,500. Qualifications Applicants should have a Ph.D. and/or M.D., with interest in model organisms, molecular biology, cell
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. Building on this platform, we combine cell biology, biochemistry, CRISPR-based approaches, organelle isolation, metabolomics and proteomics, mouse genetics, and disease models to discover principles of ER
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drugs. Our focus is on cytokine-based drugs and immune checkpoint inhibitors. We use immune competent murine models and human cell culture systems for early drug development. We also study mechanisms