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to experimentally derived disorder models and data from methods such as total scattering/pair distribution function analysis, diffuse scattering, diffraction, solid-state NMR and electron microscopy. Work closely
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Design and use custom-made antibodies to localize the expression of key elements in coelenterazine biosynthesis/recycling Use transmission electron microscopy and VolumeScope FIB-SEM electron microscopy
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of inorganic and coordination compounds, including discrete complexes and related systems, using methods such as X-ray diffraction (XRD), thermogravimetric analysis (TGA), scanning electron microscopy (SEM) and
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(confocal, electron microscopy and spatial omics) on samples. Using Seahorse and related assays to assess the impact of genome editing and drug treatment on the metabolic activity of pre-clinical models
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vesicle isolation and characterisation, such as ultracentrifugation/SEC, nanoparticle tracking analysis and electron microscopy. Small-RNA/miRNA profiling, including small RNA-seq and/or RT-qPCR. Sterile
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, structural biology, cell biology, or similar; Fluent written and spoken English skills; A background in protein biochemistry, including protein expression and purification; Experience with cryo-electron