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regulation of chemokine ligands and receptors may impact the inflammatory reaction significantly. Our incomplete understanding of complex immune reactions prohibits efficient drug development and patient
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interventions such as organ transplants or cancer treatments. Today, these progresses are challenged by the world-wide spread of drug resistant bacteria no longer responding to antibiotic treatment. The effects
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thus involved in numerous pathologies, which makes them the targets of about 36% of all FDA-approved drugs. This PhD project aims to investigate the role of GPCR mechanosensation in tissue
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