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the influence of these adaptations on interactions with other bacteria as well as pathogenesis in various infection models. The Postdoctoral Associate will be responsible for: Isolating DNA from longitudinal
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projects leverage cutting-edge techniques, including DNA barcoding, sequencing techniques, and high-throughput functional genomics. Responsibilities will include leading research projects, developing new
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innovative research that allows us: (i) to characterize soil microbiome from African soils and (ii) participate in field surveys to generate samples for DNA extraction, amplicon, and shotgun sequencing tools
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of environmental samples. Experience in advanced analytical techniques is expected, including self-directed use of approaches such as DNA/RNA sequencing, microscopy, photophysiology and environmental chemistry
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interactions are critical to protein folding, DNA base pairing, and cellular signalling. Supramolecular Chemistry applies these same principles to create artificial systems capable of performing complex tasks
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members Conduct experiments using a variety of techniques including molecular cloning, DNA mutagenesis, vector production, qPCR, RT-qPCR, Southern and Western blotting, FACS, tissue cultures, and animal
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hold a doctoral degree in biology or biomedical sciences. A combination of skills in cell culture, animal disease models, imaging, western blot, immunoprecipitation, ELISA, DNA/RNA preparation, PCR, and
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preservation (e.g., glycerol stocks, subculturing), aseptic technique, and operation under BSL-1 and BSL-2 containment requirements. Experience with microbial molecular biology techniques, including DNA/RNA
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biology approach to understand the role of modifications on histones and DNA. Towards this, we combine various experimental and computational strategies, including genome and epigenome engineering, genome
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at the molecular level. A notable discovery from the lab is that the BRD4-NUT fusion oncoprotein dysregulates DNA folding to activate oncogenic transcriptional programs. The lab has published in journals including