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Field
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cancer relapse and targeted therapy response. Responsibilities* Process and preprocess raw data across genomics, proteomics, and epigenomics platforms, including DNA-seq, RNA-seq, ChIP-seq, ATAC-seq, and
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objectives. Investigate mechanisms by which DNA damage and DNA repair defects influence innate and adaptive immune responses in cancer. Study immunogenic cell death, cytosolic nucleic acid sensing pathways
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virus neutralization assays and/or ELISAs; evaluation of vaccine potency and efficacy in swine and cattle; and use of molecular and cellular techniques such as recombinant DNA technology, DNA sequencing
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of modified ONs with advanced targeting strategies and applications in lung cancer, B-cell malignancies, and chronic inflammatory diseases. You will design and synthesise novel DNA constructs and chemical
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. The project will combine an existing dataset of approximately 200 contemporary genomes with a new time series of ancient killer whale genomes generated within the project. The tasks will include ancient DNA
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assays for microbial quantification and aptamer validation. Prepare DNA sequencing libraries, including nucleic acid extraction, amplification, and library preparation. Conduct basic bioinformatics
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: Conducting the research to address the molecular mechanisms at the atomic level that underlies the adverse effects of the environmentally-induced RNA modifications including RNA damage and m6A on DNA damage
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. Desirable experience · Analysis of epigenetic or epigenomic data, including DNA methylation or related molecular measures. · Integration of imaging with genomic, epigenomic or other molecular data using
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chronic inflammatory diseases. You will design and synthesise novel DNA constructs and chemical modifiers that selectively target cancer cells and form bioactive secondary structures. You will collaborate
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The Jiang Lab, The Icahn School of Medicine at Mount Sinai | New York City, New York | United States | 2 months ago
the defective genomic DNA, and further deliver these newly-engineered editors into targeted organs, e.g., lung, to correct the corresponding phenotypes. The position offers a competitive salary, subsidized