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alterations impact human lymphocyte development. By combining CRISPR-based genome engineering, induced pluripotent stem cells (iPSCs), and advanced thymus and bone marrow organoid systems, we study both
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– signaling – proteasome – ubiquitination – multiple myeloma – mantle cell lymphoma – cancer – immunology – inflammation – infection – streptococcus – CRISPR/Cas9 – proteomics – targeted therapy Website
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ambitious research project that bridges translational and clinical science? In our lab, your work directly contributes to science that makes a difference. The Salzer Group combines CRISPR engineering of
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mammalian cell culture, plasmid-based molecular biology, gene manipulation/CRISPR-Cas9, protein and matrix assays, and development of in vitro models. The position will work across Penn and CMCVAMC and is
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involvement across the 3 work packages (snRNAseq, vascular organoids, CRISPR validation). Chronic kidney disease (CKD) affects around 10% of the world's population and drives major vascular remodeling
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foundational support for a human genetic and immunological theory of severe infectious diseases. For more information, visit https://www.hgid.org/ About the Role We are seeking a motivated, adaptable, and team
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at https://biffilab.wordpress.com Pancreatic ductal adenocarcinoma (PDAC) remains a formidable clinical challenge. A major recent advance has been the development of KRAS inhibitors, which have shown
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genetics, gene therapy, CRISPR-based gene editing, stem cell technologies, and translational disease modelling. We are particularly interested in developing treatments for retinal disorders prevalent in
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of Biomolecular and Biomedical Science. The Chromatin Mechanisms in Disease laboratory (https://conwaychromatinlab.com/ ) at University College Dublin, led by Dr. Eric Conway, are recruiting a postdoctoral fellow
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Kang | Department of Pathology ) and review our recent publications (https://www.ncbi.nlm.nih.gov/myncbi/zizhen.kang.1/bibliography/public/ ). Applicants should have a strong background in molecular