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Research Center for Molecular Medicine (CeMM), ÖAW | Graz 12 Bez Andritz, Steiermark | Austria | 3 months ago
disease-relevant cellular phenotypes. The project combines molecular and cellular biology, mitochondrial biology, chemical biology, nutrient sensing, pharmacology, CRISPR genetics, quantitative biochemical
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, and autism. The lab combines cutting-edge molecular and optical approaches, including in vivo CRISPR genome editing, 2-photon FLIM imaging, super-resolution imaging, proteomics, and computational
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to completion of a PhD. The successful candidate will ideally have considerable experience in some of the following areas: primary human airway cell culture, handling and analysing large genomic datasets, CRISPR
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, cell culture, RNA isolation, Western blotting, CRISPR editing, transfection, and advanced microscopy are expected. Familiarity with techniques such as RNA-sequencing, RNA silencing techniques, ELISA and
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Experience: Experience in chromatin biology, DNA damage repair, or epigenetics. Experience with techniques such as protein expression/purification, CRISPR/Cas9 gene editing, and advanced microscopy is highly
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H. Lee Moffitt Cancer Center & Research Institute | Tampa, Florida | United States | about 2 months ago
, epigenomics, CRISPR-CAS9-genome editing, multiplex immunofluorescence and spatial transcriptomics, with the ultimate goal to harness the immune responses for cancer therapies. To learn more about Avram Lab
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biology, chemical biology, nutrient sensing, pharmacology, CRISPR genetics, quantitative biochemical and imaging-based readouts, and omics-based profiling, potentially including metabolomics, proteomics
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metabolism in ageing models. The use of AI and Deep Learning for data analysis and the establishment of in vitro ageing experimental systems and factor isolation using CRISPR Screening are also planned
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immunohistochemistry. Experience with design and implementation of CRISPR knock down strategies; in vivo viral transduction; single-cell RNA sequencing; and/or flow cytometry is desirable. Excellent oral and written
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, including CRISPR/Cas9, lentiviral systems, or related genome engineering approaches, is strongly preferred. Candidates should demonstrate strong experimental design and problem-solving skills, a record of