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outline The goal is to analyze the immune response to HBV following treatment with novel combination therapies, using the antiviral and an immunomodulator, in our immune competent humanized mouse model. We
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of genetic networks Interplay between chromatin architecture and gene regulation Candidates will use a combination of skills in molecular and developmental biology, instrumentation and data analysis to answer
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dynamics during regeneration, aging, and cancer, and how these processes can be modulated. Our research is primarily conducted in vivo. We combine genetic mouse models (lineage tracing, conditional
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an emphasis on tissue long lived cells such as stromal cells, and their crosstalk with tumor cells, immune cells and the vasculature. We perform mostly in vivo studies, combining lineage tracing and depletion