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. Collaboration is central to the team, both within the department and Amsterdam UMC, across the VU and UvA campuses and within the Amsterdam Neuroscience community, as well as with leading researchers worldwide
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the functional effects of generated nanobodies on GPRC5B signalling. Collaborating with POLARIS partner organisations during planned secondments and contributing to the development of nanobodies as research tools
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and apply them in clinical studies across different disease areas to generate novel biological insights. As part of the network-wide training programme, you will collaborate with leading international
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longitudinal research into patient and family outcomes. You will collaborate with clinicians, psychologists, methodologists, patient representatives and researchers across the POLARIS consortium. Through
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to assess disease mechanisms and treatment responses; analysing and interpreting experimental results and collaborating with researchers at CING and across the POLARIS consortium. You will also participate in
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embedded within the Quantitative Healthcare Analysis (qurAI) group and conducted in close collaboration with the CARA Lab and clinical partners in the Netherlands and abroad. You will work with large, multi
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fragment-based drug discovery to identify and characterise promising compounds. Contributing to the development of a functional GPCR assay pipeline and the evaluation of lead molecules in collaboration with
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. Evaluating selected candidate therapies in leukodystrophy models to assess proof-of-concept efficacy. Collaborating with researchers at InnoSer, Amsterdam UMC and other POLARIS partner organisations. Planned
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; applying behavioural and neurological phenotyping and other experimental approaches to assess disease mechanisms and treatment responses; analysing and interpreting experimental results and collaborating
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mechanisms and treatment responses; analysing and interpreting experimental results and considering how preclinical readouts can be aligned with clinically meaningful outcomes; collaborating with colleagues