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Description The postdoctoral researcher will investigate how intrinsically disordered regions and short linear motifs regulate protein interactions and cellular organization. The project will focus on protein
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Description Lipid transfer proteins mediate the distribution of lipids within an eukaryotic cell. For this, they need to interact with cellular membranes in a highly controlled and selective manner to extract
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to develop three-dimensional scaffolds that reproduce the extracellular environment of the intestine in order to improve preclinical models for drug absorption studies, toxicity testing and cell–matrix
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, expression, in vitro transcription and translation). - Biochemical approaches (protein purification, luciferase assays). - Human cell culture, handling of lentiviruses. - Development of a lentivirus-based
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://igdr.univ-rennes.fr/ team-mitochondrial-biology-and-integration-with-the-cell-cycle) focuses on state-of-the-art methods and tools in quantitative fluorescence microscopy to study the spatiotemporal
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the activity and stability of iridium oxide-based catalysts supported on various materials within a PEM electrolysis cell. Catalyst layers and membrane-electrode assemblies will be prepared and characterized in
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Information Eligibility criteria Education: PhD in tissue engineering, bioengineering or cell biology. Technical skills: experience in cell culture and organoid production, immunolabelling, PCR. Microfluidics
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in the growth of melanoma cell xenografts in isogenic mice; to determine how GATA6 modulates the tumor immune microenvironment (immunohistochemical staining of tumor sections, transcriptomic analyses
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during cell division. In eukaryotic cells, replication initiates at multiple genomic loci called replication origins, from which two replication forks propagate in opposite directions. The spatial and
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the experimental and bioinformatics analysis components—is essential. Proficiency in classical genomics techniques (RNA-seq, ChIP-seq, etc.) Proficiency in mouse ES cell culture and in vitro differentiation