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. This project is built on our recent discoveries that showing that cystine limitation stress promote pancreatic cancer tumor growth and metastasis through metabolic reprogramming. The metabolic reprogramming
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. This project is built on our recent discoveries that the actin cytoskeleton remodeling in metastatic cancer cells is able to control mitochondrial metabolism through regulating the homeostasis of mtDNA and the
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the impact of evolving hazards on the built environment and society, and fundamentally transforming the basis for which infrastructure is designed, maintained, and adapted, to ensure a prosperous and
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