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Field
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pioneered B-cell epitope peptide vaccines targeting immune checkpoint molecules and oncogenic growth factor receptors and is advancing novel multivalent and multispecific vaccine platforms toward clinical
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theoretically, in tight collaboration with experimental groups. The theoretical methods include stochastic modelling, MD simulation, and Bayesian inference; the position will also include joint collaborative
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with experience of advanced genome editing including cloning of CRISPR gRNAs for custom screens, base editing (including alternative specificity Cas enzymes) and prime editing. Experience of off-target assays
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understanding of the key molecular targets in cancer metabolism and translate it to the clinic. This position provides the opportunity of strong mentorship and a close, multidisciplinary collaborative research
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. Preferred Qualifications: Knowledge of Approximate, Local, Rényi, Bayesian differential privacy, and other related definitions. Knowledge of federated learning SOTA algorithms. Knowledge of distributed
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vulnerabilities in drug resistant, KRAS- and EGFR-mutant NSCLC and inform the development of ferroptosis-targeted treatments to improve treatment outcomes and survival for patients with lung cancer. Location
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underlying neutrophil-mediated resistance to anti-PD-1 immunotherapy Metabolic and functional reprogramming of neutrophils during cancer progression Novel therapeutic strategies targeting tumor–myeloid
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an advantage: Rodent social behaviour, empathy-related behaviour, aggression, fear, or reinforcement learning tasks. Computational modelling, Bayesian statistics, reinforcement learning models, or model-based
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(KCL), the post holder will investigate the biology of regulatory T cells (Tregs) to identify the most suppressive Treg subsets within IBD gut lesions - informing targeted strategies for restoring immune
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Establish MS-based biomarkers for target engagement and clinical studies Analyse datasets in Python/R; publish and mentor students What we offer Ownership of the LRRK2 workstream within a major international