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The GW4 BioMed3 Doctoral Landscape Programme is offering up to 18 MRC funded studentships across a range of biomedical disciplines, with a start date of October 2027. These four-year studentships provide funding for fees and stipend at the rate set by the UKRI, as well as other research training...
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Primary supervisor - Dr David Lea-Smith Engineering biology has enormous potential to address global environmental challenges like bioremediation, biosequestration, pollutant monitoring, and resource recovery. In this project, the student will apply the cutting-edge synthetic biology tools...
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modern farming, where after applying fertilizers, soil bacteria consume nitrate and generate N2O that is emitted from soil to the atmosphere. By understanding how bacteria do this and developing tools
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The project The bacterial Type 6 secretion system (T6SS) is one of the largest dynamic assemblies in Gram-negative bacteria. It shares evolutionary origins with contractile phage tails and other
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to modern medicine, and bacteriophage therapy is a promising route to treat drug-resistant infections. Yet phage therapy can fail when bacteria evolve resistance or deploy defence systems that block
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weapon against bacterial infections. These naturally occurring viruses selectively destroy harmful bacteria, offering hope where antibiotics fail. Yet a major challenge remains: how do we use phage
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major threat to human health, which is for a large part driven by plasmids (mobile pieces of DNA) that facilitate AMR gene spread between bacteria. In this project you will develop new tools based
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to modern medicine, and bacteriophage therapy is a promising route to treat drug-resistant infections. Yet phage therapy can fail when bacteria evolve resistance or deploy defence systems that block
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Gram negative bacteria such as E. coli use two main mechanisms to survive in the presence of a range of toxic molecules such as antibiotics, biocides, and solvents. First, their envelope prevents
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: Development of a mRNA PNA-FISH Spatial Transcriptomics approach applied to chronic wound biofilms; Evaluation of multispecies biofilms to understand the physiology and ecology of bacteria (Activity 2 – “Studies