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" research pole. The thesis will be supervised by Giuseppe Castagna (CNRS senior researcher, IRIF) and co-supervised by Kim Nguyen (associate professor, LMF, Université Paris-Saclay). The student will be
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contribute to NDDs. In recent years, we have identified key roles for the microtubule-associated protein Navigator-1 (NAV1) in axon growth and guidance. Notably, we have shown that NAV1 controls
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and molecular biology approaches, flow cytometry, and transcriptomic and epigenomic analyses. The ultimate goal is to identify the mechanisms driving the age-associated loss of stem cell function and to
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, the preparation and physicochemical characterization of magnetic liposomes, their association with extracellular vesicles, and the evaluation of their RNA delivery properties. Candidate Profile The project is aimed
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, including arterial stiffness, left ventricular hypertrophy and vascular calcification (VC). VC is a major cardiovascular complication of CKD, associated with a mortality risk up to 1000-fold higher than in
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of both energy resources and raw materials. 4. Methodologies The work will begin with the synthesis of ligands and transition metal complexes and the associated molecular characterisations (NMR, IR, MS
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transition metal complexes and the associated molecular characterisations (NMR, IR, MS). Advanced electrochemical studies will then be carried out to evaluate the redox properties of these complexes and their
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University of Strasbourg. The successful candidate will join the “Nanomaterials and Electron Microscopy” team within the “Surfaces and Interfaces” department, as well as the associated experimental platform
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and their associated microbial communities form an integrated functional entity—the plant holobiont—whose chemical interactions and collective metabolism play a decisive role in adapting
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associated diseases. As the laboratories comprise members of several nationalities, proficiency in English is essential. In Drosophila, approximately 12 hours after puparium formation, the head rapidly everts