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contribute to NDDs. In recent years, we have identified key roles for the microtubule-associated protein Navigator-1 (NAV1) in axon growth and guidance. Notably, we have shown that NAV1 controls
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and molecular biology approaches, flow cytometry, and transcriptomic and epigenomic analyses. The ultimate goal is to identify the mechanisms driving the age-associated loss of stem cell function and to
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, the preparation and physicochemical characterization of magnetic liposomes, their association with extracellular vesicles, and the evaluation of their RNA delivery properties. Candidate Profile The project is aimed
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, including arterial stiffness, left ventricular hypertrophy and vascular calcification (VC). VC is a major cardiovascular complication of CKD, associated with a mortality risk up to 1000-fold higher than in
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associated diseases. As the laboratories comprise members of several nationalities, proficiency in English is essential. In Drosophila, approximately 12 hours after puparium formation, the head rapidly everts
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interaction, and to determine the extent to which this synchrony is associated with the quality of the social bond between partners. To address these questions, we will study young and older adults performing
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and their associated microbial communities form an integrated functional entity—the plant holobiont—whose chemical interactions and collective metabolism play a decisive role in adapting
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, ocean acidification, shell quantity and organic-matter content on dissolution. • Characterise the microbial communities associated with the shells (16S rRNA sequencing, exposure to deep-sea bacterial
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computational approaches to integrate heterogeneous spatial, molecular and imaging data, with the aim of identifying invasion-associated metabolic niches and understanding how tumour–microenvironment interactions
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, this PhD thesis will focus on the characterization of multipolar electrograms (EGM) through graph signal processing (GSP). The underlying hypothesis is that local propagation patterns in AF are associated