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cell immunology, mucosal immunology, and cancer immunology using animal models and single-cell multiomics/spatial transcriptomics approaches. This postdoctoral researcher will combine wet-lab molecular
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compounds that enhance the activity of existing antifungal agents, reverse antifungal resistance, and reduce drug-associated toxicity. These studies build on our recent publications describing pantothenate
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-driven mathematical modeling in a transdiagnostic clinical cohort. https://impact-mh.org/awardees/impact-mh/ IMPACT-Y is collecting repeated measures from approximately 2,400 individuals across multiple
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-based perturbations, base/prime editing, and targeted epigenetic modulation). Functional genomics in neuronal systems, including transcriptomic and epigenomic profiling. Model systems such as human iPSC
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medical imaging and preclinical models are also strongly encouraged to apply. Any wet lab experience for ex vivo tracer validation studies is a plus. The successful candidate will – based on their research
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collaborative research combining functional models of acquired drug resistance with the clinical validation of novel circulating tumor DNA (ctDNA) assays. While the primary focus is wet lab experimentation
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cellular biology approaches. The Park Lab develops human stem cell-based neural models to investigate molecular and cellular mechanisms regulating neurodevelopment and neural function, and to understand how
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and cellular mechanisms underlying these disorders using cell-based assays, blood vessel organoids, and zebrafish and mouse models, working alongside neurosurgeons, computational scientists, and
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stress affects specific cell types in the nervous system and the gut, using human pluripotent stem cell (hPSC)-derived models of the enteric nervous system. Our work sits at the intersection of stem cell
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the same genetic material generate markedly different cells, and how this information is encoded within the genome. We utilize stem cells and cancer model systems, though projects range across disciplines