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research environment Preferred Qualifications Experience with organoid systems or advanced 3D culture models Experience with infection biology or immune signaling pathways Experience with in vivo disease
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are not limited to: Design and conduct biomedical experiments. Nanomaterials synthesis and characterization. Extensive experience with electrical engineering, circuit design. Translational science. 3D
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at The Pennsylvania State University. The Du lab is interested in understanding how transcription machineries and regulatory DNA elements organize in 3D in the nucleus to regulate gene expression. We leverage single
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molecular biology techniques, 2D and 3D cell culture models (hydrogels), imaging techniques (TEM, SEM, confocal), protein analysis (immunohistochemistry/immunofluorescence), and handling of rodents. Specific
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focuses are: 1) Investigating the underlying molecular mechanisms by which 3D genome topology controls the hematopoietic transcription program and lineage differentiation in normal and malignant