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. The successful candidate will leverage a combination of advanced molecular and systems neuroscience methodologies to advance our understanding of selective autophagy and lipid metabolism in glial cells
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technology platforms and 1,600 partner companies. For more information: https://www.imt-mines-ales.fr You will be affiliated with the Centre for Materials of Mines Alès (C2MA) at IMT Mines Alès and the PCH and
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ALMA MATER STUDIORUM - UNIVERSITA' DI BOLOGNA - - DIPARTIMENTO DI SCIENZE MEDICHE E CHIRURGICHE | Italy | about 2 months ago
and functionally characterized and validated in advanced 2D and 3D tumor models by assessing antitumor activity, receptor-mediated internalization, tumor penetration, and cell death mechanisms
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and Pacific Biosciences platforms, single-cell multi-omics, 3D genome architecture studies (e.g., Micro-C and HiC), CUT&RUN and CUT&Tag. Experimental systems will include CRISPR/Cas9-mediated genetic
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dedicated computing resources (3D visualization workstations, GPU servers). The research will be conducted in close collaboration with Philippe Nghe's team (Laboratory of Structural Cell Biology at École
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imaging in 2D or 3D cell culture models; electrophysiology and 3D neuronal culture. Experience in data analysis and/or statistical methods is helpful. Equipment Utilized Biosafety cabinets, liquid nitrogen
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composed of a highly interdisciplinary and international team of motivated researchers. To expand on our ability to engineer viscoelastic biomaterials and deploy them as tailorable 3D cell culture platforms
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Drosophila and/or mouse models. • Prepare and analyze samples for single-cell and/or single-nucleus sequencing approaches. • Participate in the development and use of 3D spatial transcriptomics approaches
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differentiating these stem cells into organ specific cell types and 3D organoids together with CRISPR technology, you will study how genetic variants shape cellular responses to chemical exposure. Combined with
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/ . The successful candidate will receive hands-on training in isolation and culture of different primary human cells from patient lung tissues, and in differentiation of these cells into 2D and 3D tissue-like