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that capture biological samples in their near-native 'live' state, enabling ultrastructural analysis through 3D electron tomography, Single Particle Analysis (SPA), and Correlative Light and Electron Microscopy
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, bioelectrical signalling and fibrotic cell-state transition. More information on the project can be found here: https://marcfernandezyague.com The successful candidate will conduct experiments at the Queen Mary
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without the need for additional invasive measurements. The research is embedded within the Quantitative Healthcare Analysis (qurAI) group and conducted in close collaboration with the CARA Lab and clinical
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an inclusive community of dedicated problem-solvers who hold themselves – and one another – to the highest academic and professional standards. To learn more about us, please visit https://seas.harvard.edu
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of biopsy specimens for single cell RNA-sequencing, 3D organoids, and histological analysis * Shipping of tissues to external source for sequencing * Coordination with lab staff to order necessary reagents
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on and adapt existing Python-based tools for the segmentation and analysis of compound eye structure (e.g. Currea et al. 2023, Comms Biol https://doi.org/10.1038/s42003-023-04575-x ), for application
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: Expert knowledge on coupled 3D hydrodynamic-biogeochemical models and agent-based models Expert knowledge of marine physical- and biogeochemical processes in coastal and/or open waters Very good skills in
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The spatial organisation of chromatin within the cell nucleus is crucial for the regulation of gene expression, DNA replication, and genome stability. One of the major epigenetic mechanisms influencing 3D
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to the investigated compounds, drug combinations and formulations; participation in studies using advanced cellular and tissue models, including 3D models and organoids, to evaluate therapeutic efficacy, mechanisms
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punctual mobilities within the partners of the project consortium. The PhD task will be dedicated to the 3D printing of nano-structured polymer materials by photo-Polymerization Induced Microphase Separation