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an explanation for the observed dynamics in the expression of tRNA genes. In this collaborative project, we will investigate the mechanisms of tRNA gene regulation using novel methods and technologies in human
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service research, and early stage technology assessment. It creates evidence by using comprehensive assessments and innovative modelling techniques for informed decision making regarding new and existing
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will characterize Sloppiness in cancer, investigate how it is regulated, study the impact of the resulting defective protein products on cell phenotype, and generate novel tools for cancer (immune
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considerable portion of pediatric cancers, and is not used by normal non-cancerous cells, it represents an attractive target for cancer treatment. However, the lack of comprehensive mechanistic understanding