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to an understanding of mechanisms of replication, antigenic structures, correlates of protection, and virulence properties of highly pathogenic human viruses, particularly members of the Bunyavirales order. The
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in working with T cells, B cells, or other relevant immune populations, using human samples human and/or organoids/animal models are highly encouraged to apply. There will be opportunities to work in
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at the macroscale (regional to continental), with a particular emphasis on vegetation dynamics under climate change, disturbance, and human activities. Successful candidates will engage in a variety of ongoing
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Medical Center. Research from this laboratory is focused on understanding of the mutualistic relationship between the gut microbiota and the host with implications for normal gastrointestinal development
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, Seumois G, Thomas GJ, Ganesan AP, Friedmann PS, Sanchez-Elsner T, Ay F, Ottensmeier CH, Vijayanand P. Single-cell transcriptomic analysis of tissue-resident memory T cells in human lung cancer. J Exp Med
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studies 1) “classic autoimmunity” (i.e., lupus) and 2) inborn errors of immunity (IEI) that present with autoimmunity/inflammation. Using primary human samples, in vitro cell lines, and CRISPR/Cas
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of the National Institutes of Health (NIH) and part of the Department of Health and Human Services (HHS), conducts and supports a global program of research to better understand, treat, and ultimately prevent