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Field
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, the project aims to assess the effects of PFAS on wildlife, focusing on a small freshwater fish, the mosquitofish, as a model. The project combines field and laboratory approaches to elucidate the effects
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resolution respirometry and confirmed by biochemical and molecular approach. The ability of GM1-OS will be also tested to rescue mitochondrial dysfunction in the cellular models of PD studied. Requirements
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biological matherial, and on in vitro and in vivo models. The researcher will be able to account on intestinal microbiota data, trought analys of fecal DNA and/or intestinal mucosa, analysis of immune function
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the physiological mechanisms of control of autophagy and proteostasis in cellular and murine models of acute and chronic leukemia and other onco-haematological pathologies, using common techniques of cellular and
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University of Trento – Department of Cellular, Computational and Integrative Biology | Italy | 2 months ago
enrollment sector BIO/11 (Molecular Biology). Research activities will include the development and use of disease models (possibly also 3D cell models) such as cancer, as well as the application and analysis
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mechanism of information exchange, inspired by the ionic signaling observed in biofilms. ln particular, we will develop a complex model of cells where each particle carries its own "information bit
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of Environment and Health of the Istituto Superiore di Sanità in Rome (www.genomestabilitygroup.com ). The project, funded by Worldwidecancer research, wants to investigate on the molecular mechanisms correlated
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well as on the molecular characterization of their physiological effect in in vitro models (cell lines, primary cultures and brain cells derived from patients’iPS cells), as well as on their alterations in the above
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for the creation of 3D products, as it allows us to overcome the main limitations of current additive technologies. This research is aimed at the development of numerical models based on molecular dynamics approach
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of stimuli, as an alternative to animal models, for the development of new regenerative medicine approaches in aging-related diseases (ii) to obtain biomimetic, cell-loaded, implantable scaffolds