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epithelial progenitor or stem cells. We have identified ?-catenin, HIF, and TGF? signaling as important drivers. We also study the epithelial inflammatory and host defense responses to bacterial and viral
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epithelial progenitor or stem cells. We have identified ?-catenin, HIF, and TGF? signaling as important drivers. We also study the epithelial inflammatory and host defense responses to bacterial and viral
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(including COVID-19), fibrosis, and emphysema. Specifically, we are exploring the mechanisms underlying proliferation and differentiation of alveolar epithelial progenitor or stem cells. We have identified
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) differentiation and genetic engineering to elucidate the nature of human enteric nervous system (ENS) progenitor dynamics and their crosstalk with Schwann cell precursors during ENS development and Hirschsprung
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will be human stem cell culture, lentiviral inducible overexpression of genes in pancreatic endocrine progenitor cells and differentiation to beta cells, configuring stem cell-derived beta cells
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heart. We use several different approaches to study heart regeneration, including cryoinjury model in salamanders and in vitro stem cell differentiation systems. Your mission We are seeking a highly
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sequencing technologies, single-cell imaging, optogenetics, genome engineering, induced pluripotent stem cell differentiation to neurons/organoids, and in vitro and in vivo electrophysiological measurements
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lung injury repair and tumorigenesis. We seek to understand the genetic and epigenetic basis of organ regeneration and tumorigenesis. We study the properties of stem/progenitor cells in diverse
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Investigations Towards the Early Development of Type 2 Diabetes (vivid) Impact of genotoxins on the differentiation efficacy of murine and human stem and progenitor cells and functional competence of thereof