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execute mechanistic experiments in vascular and inflammatory biology. Perform in vivo studies using murine models such as atherosclerosis, fatty liver, and acute lung injury. Conduct cell and organoid
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diseases. Research focuses include, but are not limited to, sepsis-induced cardiomyopathy, ischemic heart disease, myocardial infarction (MI), cardiac remodeling, BBB dysfunction in aging, vascular biology
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specializes in precision cardiovascular medicine, leveraging cutting-edge approaches such as human iPSC-derived 2D cardiovascular cells, 3D vascularized cardioids, CRISPR gene editing, high-throughput CRISPRko
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University of North Carolina at Chapel Hill | Chapel Hill, North Carolina | United States | about 2 months ago
increasingly aware of the central contributions of blood and vascular cell clotting activity in cancer pathogenesis. Proteins traditionally associated with blood clot formation and composition, including
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Associate for Dr. Maggirwar’s laboratory. Dr. Maggirwar’s laboratory focuses on the vascular complications associated with HIV-1 infection. Our goal is to use the immune cells isolated from the blood samples
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aspirin-responsive molecular networks. Using high-throughput multiomic approaches, the project will define aspirin-induced changes in trophoblast signaling, inflammatory pathways, and vascular regulatory
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on lung biology focused research. Required Qualifications: Highly motivated postdoctoral research with: Expertise in pulmonary vascular biology, immunology, cell, molecular, or developmental biology Prior
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using in vivo Perturb-seq. This project is related to a new NIH-funded Program Project Grant aimed at identifying differences and similarities in gene function across vascular cell types and diseases, as
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University of North Carolina at Chapel Hill | Chapel Hill, North Carolina | United States | about 2 months ago
the growth and function of the lymphatic vascular system. Our laboratory uses novel gene targeting approaches coupled with state-of-the-art phenotyping methods to address the patho-physiological roles
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mechanisms of lung transplant tolerance. It was the first laboratory to describe the mouse model of orthotopic vascularized lung transplantation and has made seminal discoveries contributing to unique