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module to limit exhaustion, gene editing (Crispr/Cas9, knocking…) includind in vivo CAR-T. We will also investigate new adoptive cell transfer in solid tumors using TRM or transgenic TCR (please see more
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endocrine tumor samples, genomic sequencing technologies, state-of-the-art high throughput signaling assays, and transgenic mouse models to study genes of interest in the mouse parathyroid. The ENRG is the
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, including tissue sectioning, immunohistochemistry, RNAscope, image analysis, PCR. Manage the transgenic mouse colony (when active), including breeding, identification, weaning, genotyping. Maintain up to date
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the canine genome, through the analysis of available genomic data, review of the scientific literature and application of selection criteria related to genomic safety, accessibility and stability of transgene
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on the kidney-lung, kidney-heart, and kidney-brain interorgan communication axes. We use in vitro assays, in vivo mouse injury models, transgenic mice, tissue analysis, confocal microscopy, and single cell or
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imaging, quantitative data analysis, and the design and maintenance of transgenic C. elegans strains. As a lab manager, the candidate will oversee wet lab operations, microscopy resources, and ordering
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focus on the kidney-lung, kidney-heart, and kidney-brain interorgan communication axes. We use in vitro assays, in vivo mouse injury models, transgenic mice, tissue analysis, confocal microscopy, and
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histology techniques, particularly with regard to the central nervous system. Experience managing transgenic animal lines, including genotyping, setting up crosses, and analyzing resulting animals. Experience
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, biochemistry, inducible transgenic, conditional knock-out and CRISPR generated knock-in mouse models, human iPSCs derived from patients, and state-of-the-art in vitro & in vivo imaging techniques. The PI’s
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on chronobiology and neuroscience related research projects. Manage transgenic and knockout mouse colonies, pup weaning and genotyping. Maintain adequate inventory of laboratory supplies; order and organize