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-adaptation of pathogenic Leptospira. Qualification: An expertise in cell biology, molecular biology, transcriptomic and genomic analysis, imaging and/or infectious models will be appreciated. Starting Date
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and biochemical characterization of bromodomain-histone interactions, analysis of Bdf1-chromatin interactions in cells by fluorescence microscopy, and transcriptomic profiling by RNA sequencing
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such as spatial transcriptomic and behavioral approaches. The selected candidate will be expected to drive the project, with the supervision and mentoring from Dr. Moyon. The ideal candidate should have
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models, flow cytometry, confocal microscopy and unbiased approaches such as single cells transcriptomics, spatial transcriptomics and epigenetics to characterize molecular and cellular mechanisms. Using
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and longitudinal data. The research may involve: clinical and biological data; electronic health records; omics: genomics, proteomics, transcriptomics and metabolomics; cellular and medical imaging
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and spatial transcriptomics and epigenomics. More details: https://research.pasteur.fr/en/team/cellular-plasticity-in-age-related-pathologies/ Candidate profiles We are seeking highly motivated
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project: High-dimensional phenotyping techniques, such as proteomics and transcriptomics, provide information on the expression of thousands of proteins or genes at the single-cell level. These advances